STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepACytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (499 aa)    
Predicted Functional Partners:
pepN
Similar to Escherichia coli aminopeptidase N PepN or B0932 SW:AMPN_ECOLI (P04825) (869 aa) fasta scores: E(): 1.6e-65, 47.052% id in 899 aa, and to Caulobacter crescentus aminopeptidase N PepN or Cc2481 SW:AMPN_CAUCR (P37893) (863 aa) fasta scores: E(): 1.3e-70, 48.946% id in 901 aa.
  
 0.943
gshB
Similar to Escherichia coli glutathione synthetase GshB or Gsh-II or B2947 SW:GSHB_ECOLI (P04425) (316 aa) fasta scores: E(): 8.5e-54, 46.77% id in 310 aa, and to Neisseria meningitidis glutathione synthetase GshB or Nma1747 TR:Q9JTJ6 (EMBL:AL162757) (318 aa) fasta scores: E(): 3.6e-64, 57.46% id in 315 aa.
   
 
 0.943
BP3107
Similar to Streptomyces coelicolor putative gamma-glutamyltranspeptidase SC3C8.26 TR:O69935 (EMBL:AL023861) (603 aa) fasta scores: E(): 3.6e-36, 31.41% id in 573 aa, and to Escherichia coli gamma-glutamyltranspeptidase precursor Ggt or B3447 SW:GGT_ECOLI () (580 aa) fasta scores: E(): 1.5e-21, 31.52% id in 533 aa.
  
  
 0.918
BP3052
Putative gamma-glutamyltranspeptidase; Similar to Mycobacterium tuberculosis CDC1551 gamma-glutamyltransferase MT0797 TR:AAK45039 (EMBL:AE006970) (512 aa) fasta scores: E(): 4.2e-112, 56.73% id in 520 aa, and to Pseudomonas sp acylase AcyI SW:PAC1_PSES3 (P15557) (557 aa) fasta scores: E(): 5.3e-37, 33.03% id in 557 aa.
   
 
 0.908
ggt
Similar to Escherichia coli gamma-glutamyltranspeptidase precursor Ggt or B3447 SW:GGT_ECOLI (P18956) (580 aa) fasta scores: E(): 1.6e-52, 35.484% id in 589 aa, and to Vibrio cholerae gamma-glutamyltranspeptidase Vc0194 TR:Q9KVF2 (EMBL:AE004109) (588 aa) fasta scores: E(): 5e-98, 49.206% id in 567 aa.
     
 0.907
BP2693
Similar to many putative gamma-glutamyltranspeptidases e.g. Mycobacterium tuberculosis putative gamma-glutamyltranspeptidase Rv0773c TR:P71828 (EMBL:Z80226) (512 aa) fasta scores: E(): 1.5e-90, 56.76% id in 525 aa. Also similar to Pseudomonas sp acylase acy 1 [includes: cephalosporin acylase SW:PAC1_PSES3 () (557 aa) fasta scores: E(): 1.1e-45, 31.81% id in 550 aa.
     
 0.907
BP2422
Similar to Rhizobium meliloti hypothetical protein Smc00586 TR:CAC45735 (EMBL:AL591786) (149 aa) fasta scores: E(): 8.8e-06, 29.8% id in 151 aa and weakly to Escherichia coli DNA polymerase III, chi subunit HolC or b4259 SW:HOLC_ECOLI (P28905) (147 aa) fasta scores: E(): 0.00013, 26.24% id in 141 aa.
  
  
 0.903
BP3007
Conserved hypothetical protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
 0.901
BP3250
Conserved hypothetical protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
 0.901
BP0598
Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
   
 
  0.900
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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