STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alcDHypothetical protein; Previously sequenced in Bordetella bronchiseptica hypothetical protein AlcD predicted to be involved in the iron siderophore alcaligin biosynthesis TR:O52832 (EMBL:AJ000061) (267 aa) fasta scores: E(): 3.7e-105, 93.63% id in 267 aa. (266 aa)    
Predicted Functional Partners:
alcC
Alcaligin biosynthesis protein; Previously sequenced in Bordetella bronchiseptica AlcC iron siderophore alcaligin biosynthesis protein TR:P94255 (EMBL:U61153) (618 aa) fasta scores: E(): 0, 99.83% id in 618 aa. Also similar to Echerichia coli aerobactin siderophore biosynthesis protein IucC SW:IUCC_ECOLI (Q47318) (580 aa) fasta scores: E(): 8.9e-46, 28.57% id in 595 aa.
 
   
 0.974
alcR
Transcriptional regulator; Previously sequenced Bordetella pertussis AlcR the regulator of alcaligin siderophore biosynthesis TR:O52066 (EMBL:AF018255) (324 aa) fasta scores: E(): 3.4e-130, 100% id in 324 aa.
 
  
 0.956
alcE
Putative iron-sulfur protein; Previously sequenced in Bordetella bronchiseptica AlcE, involved in the iron siderophore alcaligin biosynthesis, TR:O52833 (EMBL:AJ000061) (397 aa) fasta scores: E(): 7.3e-176, 99.74% id in 397 aa. Also similar to BP2804, 71.842% identity in 380 aa overlap.
     
 0.950
alcB
Alcaligin biosynthesis protein; Previously sequenced in Bordetella bronchiseptica AlcB iron siderophore alcaligin biosynthetic protein TR:P94254 (EMBL:U61153) (201 aa) fasta scores: E(): 7.8e-87, 100% id in 201 aa. Also similar to Escherichia coli aerobactin siderophore biosynthesis protein IucB SW:IUCB_ECOLI (Q47317) (315 aa) fasta scores: E(): 1.1e-05, 24.4% id in 168 aa.
 
     0.937
alcA
Alcaligin biosynthesis enzyme; Previously sequenced in Bordetella bronchiseptica alcaligin biosynthesis enzyme AlcA SW:ALCA_BORBR (Q44740) (461 aa) fasta scores: E(): 1.4e-197, 100% id in 461 aa. Also similar to Escherichia coli L-lysine 6-monooxygenase IucD or AerA SW:IUCD_ECOLI (P11295) (425 aa) fasta scores: E(): 2.5e-37, 28.97% id in 428 aa.
 
    0.906
bipA
Similar to Bordetella bronchiseptica putative outer membrane ligand binding protein BipA TR:Q9APE8 (EMBL:AF304006) (1578 aa) fasta scores: E(): 0, 79.75% id in 1576 aa, and to Escherichia coli O157:H7 EDL933 putative adhesin EaeH TR:AAG54632 (EMBL:AE005207) (1417 aa) fasta scores: E(): 1.6e-17, 23.88% id in 1390 aa. Also similar to BP3204, 41.856% identity (43.284% ungapped) in 970 aa overlap.
  
     0.772
BP2487
Hypothetical protein; Weakly similar to Aquifex aeolicus hypothetical 30.0 kDa protein Aq_362 TR:O66687 (EMBL:AE000686) (265 aa) fasta scores: E(): 1.1e-05, 29.38% id in 211 aa.
  
     0.769
BP2467
Hypothetical protein; Weakly similar to Xylella fastidiosa phage-related protein Xf0485 TR:Q9PG17 (EMBL:AE003898) (181 aa) fasta scores: E(): 3e-06, 29.18% id in 185 aa.
  
    0.754
BP3559
Putative membrane protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.743
fhaC
Hemolysin activator-like protein; Member of a two partner secretion pathway (TPS) in which it mediates the secretion of filamentous hemagglutinin FHA (fhaB). Belongs to the TPS (TC 1.B.20) family.
  
     0.723
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.