node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BP3153 | coq7 | BP3153 | BP3152 | Similar to Pseudomonas aeruginosa hypothetical protein PAa0653 TR:O05133 (EMBL:U89892) (140 aa) fasta scores: E(): 6.9e-25, 53.57% id in 140 aa. | Conserved hypothetical protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 0.548 |
BP3153 | cysM | BP3153 | BP0958 | Similar to Pseudomonas aeruginosa hypothetical protein PAa0653 TR:O05133 (EMBL:U89892) (140 aa) fasta scores: E(): 6.9e-25, 53.57% id in 140 aa. | Cysteine synthase B; Similar to Escherichia coli cysteine synthase B CysM or B2421 SW:CYSM_ECOLI (P16703) (303 aa) fasta scores: E(): 7.7e-67, 64.407% id in 295 aa, and to Pseudomonas aeruginosa cysteine synthase B CysM or Pa0932 TR:Q9I526 (EMBL:AE004527) (299 aa) fasta scores: E(): 2.2e-72, 67.442% id in 301 aa; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.421 |
BP3153 | ffh | BP3153 | BP0079 | Similar to Pseudomonas aeruginosa hypothetical protein PAa0653 TR:O05133 (EMBL:U89892) (140 aa) fasta scores: E(): 6.9e-25, 53.57% id in 140 aa. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.598 |
BP3153 | folA | BP3153 | BP3155 | Similar to Pseudomonas aeruginosa hypothetical protein PAa0653 TR:O05133 (EMBL:U89892) (140 aa) fasta scores: E(): 6.9e-25, 53.57% id in 140 aa. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.635 |
BP3153 | thyA | BP3153 | BP3154 | Similar to Pseudomonas aeruginosa hypothetical protein PAa0653 TR:O05133 (EMBL:U89892) (140 aa) fasta scores: E(): 6.9e-25, 53.57% id in 140 aa. | Putative thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.765 |
coq7 | BP3153 | BP3152 | BP3153 | Conserved hypothetical protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Similar to Pseudomonas aeruginosa hypothetical protein PAa0653 TR:O05133 (EMBL:U89892) (140 aa) fasta scores: E(): 6.9e-25, 53.57% id in 140 aa. | 0.548 |
coq7 | folA | BP3152 | BP3155 | Conserved hypothetical protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.406 |
coq7 | thyA | BP3152 | BP3154 | Conserved hypothetical protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Putative thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.448 |
cysM | BP3153 | BP0958 | BP3153 | Cysteine synthase B; Similar to Escherichia coli cysteine synthase B CysM or B2421 SW:CYSM_ECOLI (P16703) (303 aa) fasta scores: E(): 7.7e-67, 64.407% id in 295 aa, and to Pseudomonas aeruginosa cysteine synthase B CysM or Pa0932 TR:Q9I526 (EMBL:AE004527) (299 aa) fasta scores: E(): 2.2e-72, 67.442% id in 301 aa; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Similar to Pseudomonas aeruginosa hypothetical protein PAa0653 TR:O05133 (EMBL:U89892) (140 aa) fasta scores: E(): 6.9e-25, 53.57% id in 140 aa. | 0.421 |
ffh | BP3153 | BP0079 | BP3153 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Similar to Pseudomonas aeruginosa hypothetical protein PAa0653 TR:O05133 (EMBL:U89892) (140 aa) fasta scores: E(): 6.9e-25, 53.57% id in 140 aa. | 0.598 |
folA | BP3153 | BP3155 | BP3153 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Similar to Pseudomonas aeruginosa hypothetical protein PAa0653 TR:O05133 (EMBL:U89892) (140 aa) fasta scores: E(): 6.9e-25, 53.57% id in 140 aa. | 0.635 |
folA | coq7 | BP3155 | BP3152 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Conserved hypothetical protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 0.406 |
folA | thyA | BP3155 | BP3154 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Putative thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
thyA | BP3153 | BP3154 | BP3153 | Putative thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Similar to Pseudomonas aeruginosa hypothetical protein PAa0653 TR:O05133 (EMBL:U89892) (140 aa) fasta scores: E(): 6.9e-25, 53.57% id in 140 aa. | 0.765 |
thyA | coq7 | BP3154 | BP3152 | Putative thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Conserved hypothetical protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 0.448 |
thyA | folA | BP3154 | BP3155 | Putative thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.999 |