STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (210 aa)    
Predicted Functional Partners:
pdxJ
Putative efflux system outer membrane component (Pseudogene); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
  
  
 0.987
pdxK
Pyridoxine kinase; B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i.e. PNP, PLP and PMP.
  
 
 0.935
BP3252
Putative monooxygenase component; Similar to Chelatobacter heintzii nitrilotriacetate monooxygenase component B NtaB or NmoB SW:NTAB_CHEHE (P54990) (322 aa) fasta scores: E(): 8.1e-20, 38.78% id in 165 aa.
  
    0.795
BP3253
Putative conserved exported protein; Similar to Agrobacterium tumefaciens StrC58 Agr_c_4955p TR:AAK88449 (EMBL:AE008187) (367 aa) fasta scores: E(): 9.3e-78, 59.51% id in 368 aa, and to Caulobacter crescentus hypothetical protein Cc3174 TR:Q9A3M8 (EMBL:AE005981) (372 aa) fasta scores: E(): 4.1e-67, 51.64% id in 364 aa.
  
  
 0.734
BP3250
Conserved hypothetical protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
  
    0.623
purU-2
Putative formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
  
    0.580
BP3249
Putative inner membrane efflux protein; Similar to Streptomyces coelicolor putative integral membrane transport protein SCI30A.30C TR:Q9S243 (EMBL:AL096811) (463 aa) fasta scores: E(): 6.1e-19, 30.78% id in 393 aa, and to Streptoverticillium netropsis SpcT TR:Q9S1M2 (EMBL:U70376) (433 aa) fasta scores: E(): 6.8e-08, 27.29% id in 392 aa.
  
    0.574
gcvP
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
   
 0.572
putA
Bifunctional proline oxidoreductase/transcriptional repressor; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
 0.497
BP3555
Putative acetyltransferase; N-terminal region is similar to Pseudomonas aeruginosa hypothetical protein PA3685 TR:Q9HXV5 (EMBL:AE004788) (226 aa) fasta scores: E(): 3.2e-14, 40% id in 235 aa. C-terminal region is similar to Escherichia coli ribosomal-protein-alanine acetyltransferase RimI SW:RIMI_ECOLI (P09453) (148 aa) fasta scores: E(): 9.7e-10, 36.84% id in 133 aa. Full length CDS is similar to Mycobacterium leprae hypothetical protein ML0378 SW:YY21_MYCLE (Q49857) (359 aa) fasta scores: E(): 1.8e-05, 30.4% id in 375 aa.
     
 0.481
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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