STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BP3580Intracellular PHB depolymerase; Similar to Alcaligenes eutrophus intracellular poly[D(-)-3-hydroxybutyrate] (PHB) depolymerase PhaZ TR:O87189 (EMBL:AB017612) (419 aa) fasta scores: E(): 1.2e-107, 64.8% id in 412 aa, and to Rhizobium meliloti hypothetical protein SMC02770 TR:CAC41411 (EMBL:AL591782) (424 aa) fasta scores: E(): 6.4e-85, 52.69% id in 408 aa. (407 aa)    
Predicted Functional Partners:
phbC
Similar to Alcaligenes eutrophus poly-beta-hydroxybutyrate polymerase PhbC SW:PHBC_ALCEU (P23608) (589 aa) fasta scores: E(): 8.2e-129, 58.96% id in 541 aa, and to Burkholderia SpDSMZ 9242. phac TR:Q9RB82 (EMBL:AF153086) (625 aa) fasta scores: E(): 1.6e-124, 55.78% id in 545 aa.
 
  
 0.968
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.764
BP3579
Putative ferredoxin; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
       0.764
petB
Cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
      
 0.579
BP3581
Similar to Azotobacter vinelandii ferredoxin--NADP reductase Fpr SW:FENR_AZOVI (Q44532) (257 aa) fasta scores: E(): 1.4e-28, 37.59% id in 258 aa, and to Pseudomonas aeruginosa probable oxidoreductase PA4615 TR:Q9HVH6 (EMBL:AE004875) (258 aa) fasta scores: E(): 9.6e-43, 46.81% id in 267 aa. Also similar to BP1606, 40.385% identity (42.276% ungapped) in 260 aa overlap.
  
    0.579
BP1151
Conserved hypothetical protein; Similar to Alcaligenes eutrophus hypothetical 21.0 kDa protein TR:O68272 (EMBL:AF026544) (183 aa) fasta scores: E(): 2.8e-48, 73.48% id in 181 aa, and to Burkholderia spDSMZ 9242. hypothetical 21.8 kDa protein TR:Q9RB79 (EMBL:AF153086) (188 aa) fasta scores: E(): 2.1e-47, 71.5% id in 179 aa.
 
  
 0.560
BP3582
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
       0.545
BP1115
Transposase (Pseudogene); HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily.
  
    0.489
BP2948
Putative riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
  
 0.465
ribF
Similar to Escherichia coli riboflavin biosynthesis protein RibF or B0025 or Z0029 or Ecs0028 SW:RIBF_ECOLI (P08391) (313 aa) fasta scores: E(): 4e-48, 47.49% id in 299 aa, and to Pseudomonas aeruginosa riboflavin kinase/FAD synthase RibF or pa4561 TR:Q9HVM3 (EMBL:AE004869) (312 aa) fasta scores: E(): 2.6e-47, 48.48% id in 297 aa.
      
 0.448
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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