STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pncBPututative nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (405 aa)    
Predicted Functional Partners:
nadC
Similar to Mycobacterium tuberculosis nicotinate-nucleotide pyrophosphorylase [carboxylating] NadC SW:NADC_MYCTU (O06594) (285 aa) fasta scores: E(): 1.6e-36, 50.18% id in 267 aa, and to Rhizobium loti nicotinate-mononucleotide pyrophosphorylase MLL9102 TR:Q982F4 (EMBL:AP003015) (284 aa) fasta scores: E(): 2.4e-68, 71.11% id in 277 aa. Possible alternative translational start site; Belongs to the NadC/ModD family.
  
 0.981
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.980
BP3506
Conserved hypothetical protein; Similar to Escherichia coli pyrazinamidase/nicotinamidase [includes: pyrazinamidase; nicotinamidase] PncA SW:PNCA_ECOLI (P21369) (213 aa) fasta scores: E(): 2.1e-07, 31.81% id in 198 aa, and to Pseudomonas aeruginosa hypothetical protein PA4918 TR:Q9HUP5 (EMBL:AE004905) (219 aa) fasta scores: E(): 3.9e-49, 67.35% id in 193 aa.
 
 
 0.979
BP3489
Similar to Enterobacter agglomerans hypothetical protein SW:YGAD_ENTAG (P51967) (164 aa) fasta scores: E(): 7.4e-22, 50.6% id in 166 aa, and to the C-terminal region of Streptococcus pneumoniae putative competence-damage protein CinA SW:CINA_STRPN (P54184) (418 aa) fasta scores: E(): 5.1e-08, 37.33% id in 150 aa. CDS contains extra residues at the N-terminus in comparison to orthologues.
  
 
 0.925
nudC
Similar to Escherichia coli NADH pyrophosphatase NudC SW:NUDC_ECOLI (P32664) (257 aa) fasta scores: E(): 2.8e-27, 46.98% id in 166 aa. Similar to Pasteurella multocida NADH pyrophosphatase PM1735 SW:NUDC_PASMU (P57965) (264 aa) fasta scores: E(): 5e-31, 39.18% id in 245 aa.
    
 0.920
surE
Stationary-phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.903
BP1953
Putative cytochrome (Pseudogene); (CG)4 in pertussis; (CG)3 in parapertussis.
    
  0.901
BP0294
Conserved hypothetical protein (Pseudogene); Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides; Belongs to the 5'(3')-deoxyribonucleotidase family.
   
 
  0.900
ppnK
Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.749
BP3584
Similar to Haemophilus ducreyi hypothetical protein Hypo117 SW:Y117_HAEDU (O30825) (117 aa) fasta scores: E(): 3e-25, 60.17% id in 113 aa, and to Xylella fastidiosa hypothetical protein XF1711 TR:Q9PCR7 (EMBL:AE003995) (117 aa) fasta scores: E(): 6.2e-23, 59.29% id in 113 aa.
  
    0.730
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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