STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APT59925.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)    
Predicted Functional Partners:
APT59926.1
Phosphonopyruvate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.955
APT56625.1
Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.840
APT59582.1
3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.752
APT59243.1
Phosphoenolpyruvate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.706
APT59927.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
 
     0.634
APT59182.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.589
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.570
APT59924.1
Carnitine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
  
 
 0.556
APT60100.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  0.510
APT56221.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.495
Your Current Organism:
Roseomonas gilardii
NCBI taxonomy Id: 257708
Other names: ATCC 49956, CCUG 33005, CIP 104026, R. gilardii, strain 5424
Server load: low (22%) [HD]