STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_001074155_00520Unannotated protein. (422 aa)    
Predicted Functional Partners:
dltC
Unannotated protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
  
 0.992
B0177_10120
Unannotated protein; Could be involved in the transport of activated D-alanine through the membrane.
 
  
 0.991
dltA
Unannotated protein; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP-binding [...]
 
  
 0.991
acpP
Unannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
  
 0.633
acpP-2
Unannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
  
 0.633
B0177_10135
Unannotated protein.
 
     0.614
GCA_001074155_00397
Unannotated protein.
  
     0.502
B0177_10150
Unannotated protein; Belongs to the bacterial solute-binding protein 9 family.
       0.497
B0177_10140
Unannotated protein.
       0.495
B0177_10145
Unannotated protein.
       0.493
Your Current Organism:
Streptococcus pseudopneumoniae
NCBI taxonomy Id: 257758
Other names: ATCC BAA-960, ATCC:BAA:960, CCUG 49455, CIP 108659, DSM 18670, NCTC 13806, S. pseudopneumoniae, Streptococcus pseudopneumoniae Arbique et al. 2005, strain 0108
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