STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDM98796.1ADP-ribose pyrophosphatase YjhB, NUDIX family; Belongs to the Nudix hydrolase family. (134 aa)    
Predicted Functional Partners:
SDN13424.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
  0.903
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.901
SDN52178.1
Sortase, SrtB family; Belongs to the CinA family.
    
 0.872
SDM72929.1
tRNA nucleotidyltransferase (CCA-adding enzyme); Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
      0.856
SDN25785.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.856
SDN71096.1
XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.849
SDN29194.1
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.839
SDM89074.1
5-methyltetrahydrofolate--homocysteine methyltransferase.
    
 0.814
SDN93847.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
  
 
  0.802
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
    
  0.789
Your Current Organism:
Acetanaerobacterium elongatum
NCBI taxonomy Id: 258515
Other names: A. elongatum, AS 1.5012, Acetanaerobacterium elongatum Chen and Dong 2004, JCM 12359, strain Z7
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