STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaXDNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (528 aa)    
Predicted Functional Partners:
SDN68170.1
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
 
 
 0.995
SDN51093.1
DNA polymerase III, delta subunit.
   
 0.993
SDN36750.1
DNA polymerase III catalytic subunit, DnaE type.
 
 0.990
recR
DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
 0.962
SDM83659.1
Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
    
 
 0.930
SDN11460.1
DNA polymerase-3 subunit delta'.
 
  
0.891
polC
DNA polymerase-3 subunit alpha; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.888
SDN03629.1
Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.871
rnhA
Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
 0.795
SDN48061.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
 
 
 0.765
Your Current Organism:
Acetanaerobacterium elongatum
NCBI taxonomy Id: 258515
Other names: A. elongatum, AS 1.5012, Acetanaerobacterium elongatum Chen and Dong 2004, JCM 12359, strain Z7
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