STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDN64389.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (701 aa)    
Predicted Functional Partners:
SDN64430.1
Transcriptional regulator, AraC family.
     0.975
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.931
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.927
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.919
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.919
SDN99214.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
    
 0.864
SDM83825.1
DNA helicase/exodeoxyribonuclease V, subunit A; ATP-dependent DNA helicase.
  
  
  0.616
SDN24300.1
Membrane protein implicated in regulation of membrane protease activity.
   
    0.601
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
    
  0.444
SDO12769.1
Glyoxylase, beta-lactamase superfamily II.
 
     0.403
Your Current Organism:
Acetanaerobacterium elongatum
NCBI taxonomy Id: 258515
Other names: A. elongatum, AS 1.5012, Acetanaerobacterium elongatum Chen and Dong 2004, JCM 12359, strain Z7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.