| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA1596 | RPA3967 | RPA1596 | RPA3967 | Possible tryptophan synthase beta chain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative threonine dehydratase. | 0.905 |
| RPA1596 | glyA1 | RPA1596 | RPA2724 | Possible tryptophan synthase beta chain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.905 |
| RPA1596 | serB | RPA1596 | RPA2029 | Possible tryptophan synthase beta chain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative phosphoserine phosphatase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.903 |
| RPA1596 | trpA | RPA1596 | RPA0070 | Possible tryptophan synthase beta chain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.964 |
| RPA1596 | trpB | RPA1596 | RPA0069 | Possible tryptophan synthase beta chain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.917 |
| RPA1596 | trpB-1 | RPA1596 | RPA1594 | Possible tryptophan synthase beta chain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.921 |
| RPA1596 | trpC | RPA1596 | RPA2891 | Possible tryptophan synthase beta chain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Indole-3-glycerol phosphate synthase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the TrpC family. | 0.934 |
| RPA3967 | RPA1596 | RPA3967 | RPA1596 | Putative threonine dehydratase. | Possible tryptophan synthase beta chain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.905 |
| RPA3967 | glyA1 | RPA3967 | RPA2724 | Putative threonine dehydratase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.919 |
| RPA3967 | serB | RPA3967 | RPA2029 | Putative threonine dehydratase. | Putative phosphoserine phosphatase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.917 |
| RPA3967 | trpA | RPA3967 | RPA0070 | Putative threonine dehydratase. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.925 |
| RPA3967 | trpB | RPA3967 | RPA0069 | Putative threonine dehydratase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.945 |
| RPA3967 | trpB-1 | RPA3967 | RPA1594 | Putative threonine dehydratase. | Putative tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.905 |
| RPA3967 | trpC | RPA3967 | RPA2891 | Putative threonine dehydratase. | Indole-3-glycerol phosphate synthase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the TrpC family. | 0.449 |
| RPA3967 | trpG | RPA3967 | RPA4498 | Putative threonine dehydratase. | Putative lemA protein; Authentic frameshift, lemA pseudogene. | 0.562 |
| glyA1 | RPA1596 | RPA2724 | RPA1596 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Possible tryptophan synthase beta chain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.905 |
| glyA1 | RPA3967 | RPA2724 | RPA3967 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative threonine dehydratase. | 0.919 |
| glyA1 | serB | RPA2724 | RPA2029 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative phosphoserine phosphatase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.936 |
| glyA1 | trpA | RPA2724 | RPA0070 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.925 |
| glyA1 | trpB | RPA2724 | RPA0069 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.918 |