| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0168 | RPA0170 | RPA0168 | RPA0170 | Putative filament-A precursor. | Conserved hypothetical protein; COGs COG2861. | 0.716 |
| RPA0168 | ctpA | RPA0168 | RPA0169 | Putative filament-A precursor. | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | 0.949 |
| RPA0168 | nadD | RPA0168 | RPA0165 | Putative filament-A precursor. | Possible nicotinate-nucleotide adneylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.498 |
| RPA0168 | proA | RPA0168 | RPA0164 | Putative filament-A precursor. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.517 |
| RPA0168 | rlmH | RPA0168 | RPA0167 | Putative filament-A precursor. | DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.830 |
| RPA0168 | rsfS | RPA0168 | RPA0166 | Putative filament-A precursor. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.694 |
| RPA0170 | RPA0168 | RPA0170 | RPA0168 | Conserved hypothetical protein; COGs COG2861. | Putative filament-A precursor. | 0.716 |
| RPA0170 | ctpA | RPA0170 | RPA0169 | Conserved hypothetical protein; COGs COG2861. | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | 0.605 |
| RPA0170 | rlmH | RPA0170 | RPA0167 | Conserved hypothetical protein; COGs COG2861. | DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.591 |
| RPA0170 | rsfS | RPA0170 | RPA0166 | Conserved hypothetical protein; COGs COG2861. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.499 |
| RPA1166 | rlmH | RPA1166 | RPA0167 | N-6 Adenine-specific DNA methylase:Conserved hypothetical protein 95. | DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.685 |
| ctpA | RPA0168 | RPA0169 | RPA0168 | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | Putative filament-A precursor. | 0.949 |
| ctpA | RPA0170 | RPA0169 | RPA0170 | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | Conserved hypothetical protein; COGs COG2861. | 0.605 |
| ctpA | nadD | RPA0169 | RPA0165 | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | Possible nicotinate-nucleotide adneylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.592 |
| ctpA | proA | RPA0169 | RPA0164 | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.531 |
| ctpA | rlmH | RPA0169 | RPA0167 | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.849 |
| ctpA | rsfS | RPA0169 | RPA0166 | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.717 |
| engB | rlmH | RPA0631 | RPA0167 | Possible GTPases; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.587 |
| engB | rsfS | RPA0631 | RPA0166 | Possible GTPases; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.813 |
| nadD | RPA0168 | RPA0165 | RPA0168 | Possible nicotinate-nucleotide adneylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Putative filament-A precursor. | 0.498 |