| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RNR | RPA0491 | RPA3125 | RPA0491 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | Possible MgpS, ATP-dependent helicase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.516 |
| RNR | invA1 | RPA3125 | RPA0171 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.572 |
| RNR | invA2 | RPA3125 | RPA0174 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.572 |
| RNR | rlmH | RPA3125 | RPA0167 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.437 |
| RNR | ybeY | RPA3125 | RPA0446 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.859 |
| RPA0168 | RPA0170 | RPA0168 | RPA0170 | Putative filament-A precursor. | Conserved hypothetical protein; COGs COG2861. | 0.716 |
| RPA0168 | ctpA | RPA0168 | RPA0169 | Putative filament-A precursor. | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | 0.949 |
| RPA0168 | invA1 | RPA0168 | RPA0171 | Putative filament-A precursor. | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.555 |
| RPA0168 | rlmH | RPA0168 | RPA0167 | Putative filament-A precursor. | DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.830 |
| RPA0170 | RPA0168 | RPA0170 | RPA0168 | Conserved hypothetical protein; COGs COG2861. | Putative filament-A precursor. | 0.716 |
| RPA0170 | ctpA | RPA0170 | RPA0169 | Conserved hypothetical protein; COGs COG2861. | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | 0.605 |
| RPA0170 | invA1 | RPA0170 | RPA0171 | Conserved hypothetical protein; COGs COG2861. | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.706 |
| RPA0170 | rlmH | RPA0170 | RPA0167 | Conserved hypothetical protein; COGs COG2861. | DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.591 |
| RPA0491 | RNR | RPA0491 | RPA3125 | Possible MgpS, ATP-dependent helicase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.516 |
| RPA0491 | invA1 | RPA0491 | RPA0171 | Possible MgpS, ATP-dependent helicase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.599 |
| RPA0491 | invA2 | RPA0491 | RPA0174 | Possible MgpS, ATP-dependent helicase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.557 |
| RPA0491 | yjeF | RPA0491 | RPA2965 | Possible MgpS, ATP-dependent helicase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Protein of unknown function UPF0031:YjeF-related protein, N-terminal; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hyd [...] | 0.831 |
| ctpA | RPA0168 | RPA0169 | RPA0168 | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | Putative filament-A precursor. | 0.949 |
| ctpA | RPA0170 | RPA0169 | RPA0170 | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | Conserved hypothetical protein; COGs COG2861. | 0.605 |
| ctpA | invA1 | RPA0169 | RPA0171 | Putative periplasmic carboxyl-terminal processing protease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the peptidase S41A family. | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.638 |