| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA2093 | fumA | RPA2093 | RPA3876 | Conserved hypothetical protein; COGs COG1053. | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.928 |
| RPA2093 | fumC1 | RPA2093 | RPA1329 | Conserved hypothetical protein; COGs COG1053. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.647 |
| RPA2093 | fumC2 | RPA2093 | RPA3500 | Conserved hypothetical protein; COGs COG1053. | Fumarate hydratase C; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.647 |
| RPA2093 | sdhB | RPA2093 | RPA0216 | Conserved hypothetical protein; COGs COG1053. | Succinate dehydrogenase iron-sulfur protein subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.982 |
| RPA2093 | sdhC | RPA2093 | RPA0219 | Conserved hypothetical protein; COGs COG1053. | Succinate dehydrogenase membrane anchor/cytochrome b subunit. | 0.977 |
| RPA2093 | sdhD | RPA2093 | RPA0218 | Conserved hypothetical protein; COGs COG1053. | Succinate dehydrogenase cytochrome b small subunit. | 0.954 |
| RPA2093 | sucC | RPA2093 | RPA0191 | Conserved hypothetical protein; COGs COG1053. | succinyl-coA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.810 |
| RPA2093 | sucD | RPA2093 | RPA0190 | Conserved hypothetical protein; COGs COG1053. | succinyl-CoA synthetase alpha-subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.745 |
| RPA2340 | fumA | RPA2340 | RPA3876 | Putative membrane protein. | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.928 |
| RPA2340 | fumC1 | RPA2340 | RPA1329 | Putative membrane protein. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.636 |
| RPA2340 | fumC2 | RPA2340 | RPA3500 | Putative membrane protein. | Fumarate hydratase C; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.636 |
| RPA2340 | sdhB | RPA2340 | RPA0216 | Putative membrane protein. | Succinate dehydrogenase iron-sulfur protein subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.976 |
| RPA2340 | sdhC | RPA2340 | RPA0219 | Putative membrane protein. | Succinate dehydrogenase membrane anchor/cytochrome b subunit. | 0.975 |
| RPA2340 | sdhD | RPA2340 | RPA0218 | Putative membrane protein. | Succinate dehydrogenase cytochrome b small subunit. | 0.952 |
| RPA2340 | sucC | RPA2340 | RPA0191 | Putative membrane protein. | succinyl-coA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.791 |
| RPA2340 | sucD | RPA2340 | RPA0190 | Putative membrane protein. | succinyl-CoA synthetase alpha-subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.693 |
| fumA | RPA2093 | RPA3876 | RPA2093 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Conserved hypothetical protein; COGs COG1053. | 0.928 |
| fumA | RPA2340 | RPA3876 | RPA2340 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Putative membrane protein. | 0.928 |
| fumA | fumC1 | RPA3876 | RPA1329 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.986 |
| fumA | fumC2 | RPA3876 | RPA3500 | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarate hydratase C; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.973 |