STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuBBeta-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (370 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.999
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 0.998
ilvH
Acetolactate synthase (small subunit); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
 0.997
ilvI
Acetolactate synthase (large subunit); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 0.974
RPA3917
Possible acetolactate synthase large subunit; Belongs to the TPP enzyme family.
 0.963
ilvB
Putative acetolactate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the TPP enzyme family.
 0.960
RPA4054
Possible acetolactate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the TPP enzyme family.
 0.952
RPA3967
Putative threonine dehydratase.
 
 
 0.950
ilvX
Putative acetolactate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
  
 0.938
RPA2001
Putative acetolactate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
  
 0.938
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
Server load: low (36%) [HD]