| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0955 | mazG | RPA0955 | RPA2811 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Possible mazG. | 0.907 |
| RPA0955 | pyrF | RPA0955 | RPA0337 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.905 |
| RPA0955 | pyrH | RPA0955 | RPA2920 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.901 |
| RPA0955 | surE | RPA0955 | RPA2841 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Survival protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.919 |
| carA | carB | RPA1276 | RPA4071 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | 0.999 |
| carA | pyr | RPA1276 | RPA3118 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Putative noncatalytic chain of dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.992 |
| carA | pyrB | RPA1276 | RPA3117 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Aspartate carbamoyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carA | pyrE | RPA1276 | RPA4724 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Putative uridine 5-monophosphate synthase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.924 |
| carA | pyrF | RPA1276 | RPA0337 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.915 |
| carA | uraI | RPA1276 | RPA0797 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.944 |
| carB | carA | RPA4071 | RPA1276 | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | 0.999 |
| carB | pyr | RPA4071 | RPA3118 | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | Putative noncatalytic chain of dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.992 |
| carB | pyrB | RPA4071 | RPA3117 | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | Aspartate carbamoyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB | pyrE | RPA4071 | RPA4724 | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | Putative uridine 5-monophosphate synthase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.947 |
| carB | pyrF | RPA4071 | RPA0337 | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.935 |
| carB | pyrH | RPA4071 | RPA2920 | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.412 |
| carB | uraI | RPA4071 | RPA0797 | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.960 |
| mazG | RPA0955 | RPA2811 | RPA0955 | Possible mazG. | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | 0.907 |
| mazG | pyrF | RPA2811 | RPA0337 | Possible mazG. | Orotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.900 |
| mazG | pyrH | RPA2811 | RPA2920 | Possible mazG. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.901 |