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glnDProtein PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. (949 aa)    
Predicted Functional Partners:
glnB
Nitrogen regulatory protein P-II; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the P(II) protein family.
 
 
 0.990
ntrB
Nitrogen regulatory signal transduction histidine kinase NtrB; Observed by proteomics; Citation: Foster-Hartnett et al. (1993) Mol. Microbiol. 8:903-914.
  
 
 
 0.897
glnE
Putative glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the sign [...]
 
   
 0.877
ntrC
Nitrogen assimilation regulatory protein ntrC Response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
  
   
 0.806
glnK1
GlnK, nitrogen regulatory protein P-II; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the P(II) protein family.
 
 
 
 0.721
glnK2
GlnK, nitrogen regulatory protein P-II; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the P(II) protein family.
 
 
 
 0.717
glnA-2
Glutamine synthetase II; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
     
 0.698
gltB
Glutamate synthase, large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
     
 0.680
glnA
Glutamine synthetase I; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
   
 0.666
bamA
Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
    0.630
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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