| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA3394 | rnpA | RPA3394 | RPA0633 | DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.943 |
| RPA3394 | rplD | RPA3394 | RPA3249 | DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.656 |
| RPA3394 | rpmH, | RPA3394 | RPA0634 | DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Possible ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.667 |
| RPA3394 | yidC | RPA3394 | RPA0632 | DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 60 kDa inner membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.895 |
| rnpA | RPA3394 | RPA0633 | RPA3394 | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.943 |
| rnpA | rplC | RPA0633 | RPA3250 | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.887 |
| rnpA | rplD | RPA0633 | RPA3249 | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.946 |
| rnpA | rpmH, | RPA0633 | RPA0634 | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Possible ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.985 |
| rnpA | rpsA | RPA0633 | RPA0064 | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity); Belongs to the bacterial ribosomal protein bS1 family. | 0.882 |
| rnpA | rpsJ | RPA0633 | RPA3251 | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. | 0.893 |
| rnpA | rpsL | RPA0633 | RPA3255 | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.880 |
| rnpA | rpsT | RPA0633 | RPA4836 | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA; Belongs to the bacterial ribosomal protein bS20 family. | 0.881 |
| rnpA | rpsU,-2 | RPA0633 | RPA4176 | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Ribosomal protein S21; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.908 |
| rnpA | yidC | RPA0633 | RPA0632 | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 60 kDa inner membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.986 |
| rplC | rnpA | RPA3250 | RPA0633 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Probable ribonuclease p protein component (protein c5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.887 |
| rplC | rplD | RPA3250 | RPA3249 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.999 |
| rplC | rpmH, | RPA3250 | RPA0634 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Possible ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.939 |
| rplC | rpsA | RPA3250 | RPA0064 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity); Belongs to the bacterial ribosomal protein bS1 family. | 0.988 |
| rplC | rpsJ | RPA3250 | RPA3251 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. | 0.999 |
| rplC | rpsL | RPA3250 | RPA3255 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.995 |