| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0030 | RPA0636 | RPA0030 | RPA0636 | Bacterial Sun/eukaryotic nucleolar Nop1/Nop2; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Hypothetical protein. | 0.723 |
| RPA0030 | RPA3200 | RPA0030 | RPA3200 | Bacterial Sun/eukaryotic nucleolar Nop1/Nop2; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Putative dual serine/threonine-protein kinase/phosphatase. | 0.732 |
| RPA0030 | priA | RPA0030 | RPA0181 | Bacterial Sun/eukaryotic nucleolar Nop1/Nop2; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Putative priA family helicase (primosomal protein N', replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.433 |
| RPA0030 | thyA | RPA0030 | RPA3493 | Bacterial Sun/eukaryotic nucleolar Nop1/Nop2; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.561 |
| RPA0636 | RPA0030 | RPA0636 | RPA0030 | Hypothetical protein. | Bacterial Sun/eukaryotic nucleolar Nop1/Nop2; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.723 |
| RPA0636 | RPA0637 | RPA0636 | RPA0637 | Hypothetical protein. | Hypothetical protein. | 0.693 |
| RPA0636 | RPA2202 | RPA0636 | RPA2202 | Hypothetical protein. | SUN-family protein, putative RNA methyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.723 |
| RPA0636 | RPA3200 | RPA0636 | RPA3200 | Hypothetical protein. | Putative dual serine/threonine-protein kinase/phosphatase. | 0.833 |
| RPA0636 | def | RPA0636 | RPA0621 | Hypothetical protein. | Putative N-formylmethionylaminoacyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.581 |
| RPA0636 | folD | RPA0636 | RPA0413 | Hypothetical protein. | Putative methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.635 |
| RPA0636 | mcyE | RPA0636 | RPA3339 | Hypothetical protein. | Possible McyE polykeitde synthase and peptide synthetase (AF183408). | 0.673 |
| RPA0636 | nusB | RPA0636 | RPA2729 | Hypothetical protein. | Antitermination factor, NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.789 |
| RPA0636 | priA | RPA0636 | RPA0181 | Hypothetical protein. | Putative priA family helicase (primosomal protein N', replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.657 |
| RPA0636 | thyA | RPA0636 | RPA3493 | Hypothetical protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.520 |
| RPA0637 | RPA0636 | RPA0637 | RPA0636 | Hypothetical protein. | Hypothetical protein. | 0.693 |
| RPA2202 | RPA0636 | RPA2202 | RPA0636 | SUN-family protein, putative RNA methyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Hypothetical protein. | 0.723 |
| RPA2202 | RPA3200 | RPA2202 | RPA3200 | SUN-family protein, putative RNA methyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Putative dual serine/threonine-protein kinase/phosphatase. | 0.732 |
| RPA2202 | thyA | RPA2202 | RPA3493 | SUN-family protein, putative RNA methyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.561 |
| RPA3200 | RPA0030 | RPA3200 | RPA0030 | Putative dual serine/threonine-protein kinase/phosphatase. | Bacterial Sun/eukaryotic nucleolar Nop1/Nop2; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.732 |
| RPA3200 | RPA0636 | RPA3200 | RPA0636 | Putative dual serine/threonine-protein kinase/phosphatase. | Hypothetical protein. | 0.833 |