| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0422 | RPA0789 | RPA0422 | RPA0789 | Possible dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Putative serine-glyoxylate aminotransferase. | 0.934 |
| RPA0422 | glcB | RPA0422 | RPA4216 | Possible dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.917 |
| RPA0422 | glcF | RPA0422 | RPA1132 | Possible dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Glycolate oxidase subunit, (Fe-S)protein, GlcF. | 0.909 |
| RPA0789 | RPA0422 | RPA0789 | RPA0422 | Putative serine-glyoxylate aminotransferase. | Possible dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.934 |
| RPA0789 | RPA3967 | RPA0789 | RPA3967 | Putative serine-glyoxylate aminotransferase. | Putative threonine dehydratase. | 0.930 |
| RPA0789 | gcvP | RPA0789 | RPA3850 | Putative serine-glyoxylate aminotransferase. | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.937 |
| RPA0789 | gcvT2 | RPA0789 | RPA3848 | Putative serine-glyoxylate aminotransferase. | Glycine cleavage system protein T2; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.933 |
| RPA0789 | glcB | RPA0789 | RPA4216 | Putative serine-glyoxylate aminotransferase. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.929 |
| RPA0789 | glcF | RPA0789 | RPA1132 | Putative serine-glyoxylate aminotransferase. | Glycolate oxidase subunit, (Fe-S)protein, GlcF. | 0.932 |
| RPA0789 | glyA1 | RPA0789 | RPA2724 | Putative serine-glyoxylate aminotransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.931 |
| RPA0789 | glyA2 | RPA0789 | RPA2796 | Putative serine-glyoxylate aminotransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.931 |
| RPA0789 | lldA | RPA0789 | RPA4320 | Putative serine-glyoxylate aminotransferase. | L-lactate dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.949 |
| RPA0789 | serB | RPA0789 | RPA2029 | Putative serine-glyoxylate aminotransferase. | Putative phosphoserine phosphatase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.936 |
| RPA3967 | RPA0789 | RPA3967 | RPA0789 | Putative threonine dehydratase. | Putative serine-glyoxylate aminotransferase. | 0.930 |
| RPA3967 | gcvP | RPA3967 | RPA3850 | Putative threonine dehydratase. | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.512 |
| RPA3967 | glyA1 | RPA3967 | RPA2724 | Putative threonine dehydratase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.919 |
| RPA3967 | glyA2 | RPA3967 | RPA2796 | Putative threonine dehydratase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.919 |
| RPA3967 | serB | RPA3967 | RPA2029 | Putative threonine dehydratase. | Putative phosphoserine phosphatase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.917 |
| gcvP | RPA0789 | RPA3850 | RPA0789 | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative serine-glyoxylate aminotransferase. | 0.937 |
| gcvP | RPA3967 | RPA3850 | RPA3967 | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative threonine dehydratase. | 0.512 |