| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA3661 | relA | RPA3661 | RPA2693 | Metal dependent phosphohydrolase. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.603 |
| RPA3661 | rnk | RPA3661 | RPA0866 | Metal dependent phosphohydrolase. | Putative nucleoside diphosphate kinase regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.560 |
| RPA3661 | rpsO | RPA3661 | RPA0433 | Metal dependent phosphohydrolase. | Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. Belongs to the universal ribosomal protein uS15 family. | 0.808 |
| dut | nrd | RPA0080 | RPA2977 | Putative deoxyuridine 5'triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.773 |
| dut | rnk | RPA0080 | RPA0866 | Putative deoxyuridine 5'triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Putative nucleoside diphosphate kinase regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.593 |
| nrd | dut | RPA2977 | RPA0080 | Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Putative deoxyuridine 5'triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.773 |
| nrd | relA | RPA2977 | RPA2693 | Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.903 |
| nrd | rnk | RPA2977 | RPA0866 | Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Putative nucleoside diphosphate kinase regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.560 |
| pnp | rnk | RPA0432 | RPA0866 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Putative nucleoside diphosphate kinase regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.584 |
| pnp | rpoA | RPA0432 | RPA3226 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.894 |
| pnp | rpoB | RPA0432 | RPA3268 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.930 |
| pnp | rpoC | RPA0432 | RPA3267 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.749 |
| pnp | rpsO | RPA0432 | RPA0433 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. Belongs to the universal ribosomal protein uS15 family. | 0.875 |
| relA | RPA3661 | RPA2693 | RPA3661 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Metal dependent phosphohydrolase. | 0.603 |
| relA | nrd | RPA2693 | RPA2977 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.903 |
| relA | rnk | RPA2693 | RPA0866 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative nucleoside diphosphate kinase regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.560 |
| relA | rnpO | RPA2693 | RPA2692 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.801 |
| relA | rpsO | RPA2693 | RPA0433 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. Belongs to the universal ribosomal protein uS15 family. | 0.808 |
| rnk | RPA3661 | RPA0866 | RPA3661 | Putative nucleoside diphosphate kinase regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Metal dependent phosphohydrolase. | 0.560 |
| rnk | dut | RPA0866 | RPA0080 | Putative nucleoside diphosphate kinase regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative deoxyuridine 5'triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.593 |