Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hupEPutative membrane-bound hydrogenase component hupE. (197 aa)    
Predicted Functional Partners:
RPA4757
Possible outer membrane receptor for iron transport.
 
    
 0.899
hupD
Hydrogenase maturation protein hupD.
  
  
 0.829
hupF
Hydrogenase expression/formation protein hupF.
  
  
 0.792
CbiG
Cobalamin biosynthesis protein G; CbiG.
     
 0.777
cobN
Putative cobaltochelatase subunit CobN.
     
 0.760
cobW
Putative cobalamin synthesis protein cobW; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
     
 0.744
nxiA,
Putative high-affinity nickel-transport protein; Belongs to the NiCoT transporter (TC 2.A.52) family.
      
 0.740
ureB
Urease beta subunit; Belongs to the urease beta subunit family.
 
  
 0.653
hupC
Ni/Fe-hydrogenase 1 B-type cytochrome subunit.
  
    0.650
cysG
Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
 0.646
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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