STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hupEPutative membrane-bound hydrogenase component hupE. (197 aa)    
Predicted Functional Partners:
RPA4757
Possible outer membrane receptor for iron transport.
 
 
  
 0.899
hupD
Hydrogenase maturation protein hupD.
  
  
 0.826
hupF
Hydrogenase expression/formation protein hupF.
  
  
 0.800
CbiG
Cobalamin biosynthesis protein G; CbiG.
  
  
 0.743
cobN
Putative cobaltochelatase subunit CobN.
     
 0.737
cobW
Putative cobalamin synthesis protein cobW; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
  
  
 0.732
cobO,
Putative cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
     
 0.719
cysG
Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
 0.717
nxiA,
Putative high-affinity nickel-transport protein; Belongs to the NiCoT transporter (TC 2.A.52) family.
   
  
 0.714
hupL
Hydrogenase large chain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
  
 0.637
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.