| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CbiG | cobN | RPA2085 | RPA0716 | Cobalamin biosynthesis protein G; CbiG. | Putative cobaltochelatase subunit CobN. | 0.686 |
| CbiG | cobW | RPA2085 | RPA0715 | Cobalamin biosynthesis protein G; CbiG. | Putative cobalamin synthesis protein cobW; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.782 |
| CbiG | cysG | RPA2085 | RPA4215 | Cobalamin biosynthesis protein G; CbiG. | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.881 |
| CbiG | hupE | RPA2085 | RPA0966 | Cobalamin biosynthesis protein G; CbiG. | Putative membrane-bound hydrogenase component hupE. | 0.777 |
| RPA4757 | hupE | RPA4757 | RPA0966 | Possible outer membrane receptor for iron transport. | Putative membrane-bound hydrogenase component hupE. | 0.899 |
| cobN | CbiG | RPA0716 | RPA2085 | Putative cobaltochelatase subunit CobN. | Cobalamin biosynthesis protein G; CbiG. | 0.686 |
| cobN | cobW | RPA0716 | RPA0715 | Putative cobaltochelatase subunit CobN. | Putative cobalamin synthesis protein cobW; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.952 |
| cobN | cysG | RPA0716 | RPA4215 | Putative cobaltochelatase subunit CobN. | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.727 |
| cobN | hupE | RPA0716 | RPA0966 | Putative cobaltochelatase subunit CobN. | Putative membrane-bound hydrogenase component hupE. | 0.760 |
| cobW | CbiG | RPA0715 | RPA2085 | Putative cobalamin synthesis protein cobW; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Cobalamin biosynthesis protein G; CbiG. | 0.782 |
| cobW | cobN | RPA0715 | RPA0716 | Putative cobalamin synthesis protein cobW; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative cobaltochelatase subunit CobN. | 0.952 |
| cobW | hupE | RPA0715 | RPA0966 | Putative cobalamin synthesis protein cobW; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative membrane-bound hydrogenase component hupE. | 0.744 |
| cysG | CbiG | RPA4215 | RPA2085 | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Cobalamin biosynthesis protein G; CbiG. | 0.881 |
| cysG | cobN | RPA4215 | RPA0716 | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Putative cobaltochelatase subunit CobN. | 0.727 |
| cysG | hupE | RPA4215 | RPA0966 | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Putative membrane-bound hydrogenase component hupE. | 0.646 |
| hupC | hupD | RPA0964 | RPA0965 | Ni/Fe-hydrogenase 1 B-type cytochrome subunit. | Hydrogenase maturation protein hupD. | 0.992 |
| hupC | hupE | RPA0964 | RPA0966 | Ni/Fe-hydrogenase 1 B-type cytochrome subunit. | Putative membrane-bound hydrogenase component hupE. | 0.650 |
| hupC | hupF | RPA0964 | RPA0967 | Ni/Fe-hydrogenase 1 B-type cytochrome subunit. | Hydrogenase expression/formation protein hupF. | 0.947 |
| hupD | hupC | RPA0965 | RPA0964 | Hydrogenase maturation protein hupD. | Ni/Fe-hydrogenase 1 B-type cytochrome subunit. | 0.992 |
| hupD | hupE | RPA0965 | RPA0966 | Hydrogenase maturation protein hupD. | Putative membrane-bound hydrogenase component hupE. | 0.829 |