Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
RPA1026Possible adenine DNA methyltransferase; Belongs to the N(4)/N(6)-methyltransferase family. (376 aa)    
Predicted Functional Partners:
lexA
SOS response transcriptional repressor, lexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
 0.965
RPA4774
Conserved unknown protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
   
 0.793
RPA0828
Transcriptional regulator, MarR family.
      
 0.741
nnrR
Putative nitric oxide responsive transcriptional regulator NnrR, Crp/Fnr family.
      
 0.741
fixK2
Nitrogen fixation transcriptional regulator fixK2, Crp/Fnr family.
      
 0.740
RPA0500
Heat shock protein DnaJ, N-terminal.
  
 
   0.634
sucC
succinyl-coA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
    0.605
RPA0556
HNH endonuclease:HNH nuclease.
 
  
 0.591
cobT2
cobT protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
    0.573
ntrC
Nitrogen assimilation regulatory protein ntrC Response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
      
 0.558
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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