| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0955 | RPA1065 | RPA0955 | RPA1065 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Metal dependent phosphohydrolase. | 0.906 |
| RPA0955 | RPA1101 | RPA0955 | RPA1101 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Putative cytidine deaminase. | 0.914 |
| RPA0955 | RPA2855 | RPA0955 | RPA2855 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. | 0.901 |
| RPA0955 | RPA4147 | RPA0955 | RPA4147 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Putative nucleoside phosphorylase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.912 |
| RPA0955 | cmk | RPA0955 | RPA0063 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Cytidylate monophosphate kinase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.900 |
| RPA0955 | dut | RPA0955 | RPA0080 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Putative deoxyuridine 5'triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.902 |
| RPA0955 | kguA | RPA0955 | RPA3069 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.903 |
| RPA0955 | surE | RPA0955 | RPA2841 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Survival protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
| RPA0955 | thyA | RPA0955 | RPA3493 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.910 |
| RPA0955 | tmk | RPA0955 | RPA2775 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.939 |
| RPA1065 | RPA0955 | RPA1065 | RPA0955 | Metal dependent phosphohydrolase. | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | 0.906 |
| RPA1065 | RPA1101 | RPA1065 | RPA1101 | Metal dependent phosphohydrolase. | Putative cytidine deaminase. | 0.901 |
| RPA1065 | RPA2855 | RPA1065 | RPA2855 | Metal dependent phosphohydrolase. | dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. | 0.914 |
| RPA1065 | RPA4147 | RPA1065 | RPA4147 | Metal dependent phosphohydrolase. | Putative nucleoside phosphorylase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.905 |
| RPA1065 | cmk | RPA1065 | RPA0063 | Metal dependent phosphohydrolase. | Cytidylate monophosphate kinase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.903 |
| RPA1065 | dut | RPA1065 | RPA0080 | Metal dependent phosphohydrolase. | Putative deoxyuridine 5'triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.916 |
| RPA1065 | kguA | RPA1065 | RPA3069 | Metal dependent phosphohydrolase. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.905 |
| RPA1065 | surE | RPA1065 | RPA2841 | Metal dependent phosphohydrolase. | Survival protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
| RPA1065 | thyA | RPA1065 | RPA3493 | Metal dependent phosphohydrolase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.905 |
| RPA1065 | tmk | RPA1065 | RPA2775 | Metal dependent phosphohydrolase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.906 |