| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA1076 | RPA1077 | RPA1076 | RPA1077 | Putative oxidoreductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.592 |
| RPA1077 | RPA1076 | RPA1077 | RPA1076 | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative oxidoreductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.592 |
| RPA1077 | RPA1078 | RPA1077 | RPA1078 | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Probable transcriptional regulator, AraC family. | 0.517 |
| RPA1077 | cysQ | RPA1077 | RPA1625 | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative CysQ protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.639 |
| RPA1077 | gcp | RPA1077 | RPA0255 | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative o-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.516 |
| RPA1077 | glmS | RPA1077 | RPA2660 | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.529 |
| RPA1077 | hemK | RPA1077 | RPA0607 | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative protoporphyrinogen oxidase, hemK protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.730 |
| RPA1077 | manC, | RPA1077 | RPA3322 | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative mannose-1-phosphate guanylyltransferase (GDP) (GDP-mannose pyrophosphorylase) (GMP); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.512 |
| RPA1077 | polA | RPA1077 | RPA4723 | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.551 |
| RPA1077 | pyrG | RPA1077 | RPA2886 | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.528 |
| RPA1077 | rho | RPA1077 | RPA0296 | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Transcription termination factor rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.520 |
| RPA1078 | RPA1077 | RPA1078 | RPA1077 | Probable transcriptional regulator, AraC family. | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.517 |
| cysQ | RPA1077 | RPA1625 | RPA1077 | Putative CysQ protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.639 |
| gcp | RPA1077 | RPA0255 | RPA1077 | Putative o-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.516 |
| gcp | polA | RPA0255 | RPA4723 | Putative o-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.552 |
| gcp | pyrG | RPA0255 | RPA2886 | Putative o-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.488 |
| glmS | RPA1077 | RPA2660 | RPA1077 | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Sua5/YciO/YrdC/YwlC protein family:SUA5 domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.529 |
| glmS | manC, | RPA2660 | RPA3322 | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Putative mannose-1-phosphate guanylyltransferase (GDP) (GDP-mannose pyrophosphorylase) (GMP); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.942 |
| glmS | polA | RPA2660 | RPA4723 | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.424 |
| glmS | pyrG | RPA2660 | RPA2886 | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.583 |