| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA4722 | carA | RPA4722 | RPA1276 | Possible glutamate synthase, small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | 0.988 |
| RPA4722 | carB | RPA4722 | RPA4071 | Possible glutamate synthase, small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | 0.992 |
| RPA4722 | purF | RPA4722 | RPA3091 | Possible glutamate synthase, small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.930 |
| RPA4722 | purL | RPA4722 | RPA3818 | Possible glutamate synthase, small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.912 |
| RPA4722 | pyr | RPA4722 | RPA3118 | Possible glutamate synthase, small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative noncatalytic chain of dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.822 |
| RPA4722 | pyrB | RPA4722 | RPA3117 | Possible glutamate synthase, small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Aspartate carbamoyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.936 |
| RPA4722 | pyrC | RPA4722 | RPA1069 | Possible glutamate synthase, small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Possible dihydroorotase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.822 |
| RPA4722 | pyrE | RPA4722 | RPA4724 | Possible glutamate synthase, small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative uridine 5-monophosphate synthase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.894 |
| RPA4722 | uraI | RPA4722 | RPA0797 | Possible glutamate synthase, small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.992 |
| argF | carA | RPA4772 | RPA1276 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | 0.996 |
| argF | carB | RPA4772 | RPA4071 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | 0.996 |
| argF | pyr | RPA4772 | RPA3118 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Putative noncatalytic chain of dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.931 |
| argF | pyrB | RPA4772 | RPA3117 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Aspartate carbamoyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.888 |
| argF | pyrC | RPA4772 | RPA1069 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | Possible dihydroorotase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.930 |
| carA | RPA4722 | RPA1276 | RPA4722 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Possible glutamate synthase, small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.988 |
| carA | argF | RPA1276 | RPA4772 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.996 |
| carA | carB | RPA1276 | RPA4071 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Carbamoyl-phosphate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarB family. | 0.999 |
| carA | purF | RPA1276 | RPA3091 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.980 |
| carA | purL | RPA1276 | RPA3818 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.958 |
| carA | pyr | RPA1276 | RPA3118 | Carbamoyl-phosphate synthase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the CarA family. | Putative noncatalytic chain of dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.993 |