| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0135 | RPA4536 | RPA0135 | RPA4536 | Possible oxidoreductase. | Cyclic nucleotide regulated pyridine nucleotide-disulphide oxidoreductase. | 0.454 |
| RPA0135 | cyaA | RPA0135 | RPA1582 | Possible oxidoreductase. | Ferredoxin:Adenylate/Guanylate cyclase. | 0.939 |
| RPA0135 | nuoCD | RPA0135 | RPA4262 | Possible oxidoreductase. | NADH-ubiquinone dehydrogenase chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.999 |
| RPA2271 | RPA4536 | RPA2271 | RPA4536 | Putative Pyruvate kinase; Belongs to the pyruvate kinase family. | Cyclic nucleotide regulated pyridine nucleotide-disulphide oxidoreductase. | 0.406 |
| RPA2271 | cyaA | RPA2271 | RPA1582 | Putative Pyruvate kinase; Belongs to the pyruvate kinase family. | Ferredoxin:Adenylate/Guanylate cyclase. | 0.910 |
| RPA2271 | mazG | RPA2271 | RPA2811 | Putative Pyruvate kinase; Belongs to the pyruvate kinase family. | Possible mazG. | 0.900 |
| RPA2271 | ndk | RPA2271 | RPA3056 | Putative Pyruvate kinase; Belongs to the pyruvate kinase family. | Nucleoside-diphosphate-kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.910 |
| RPA2271 | pyk | RPA2271 | RPA4193 | Putative Pyruvate kinase; Belongs to the pyruvate kinase family. | Pyruvate kinase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pyruvate kinase family. | 0.926 |
| RPA2271 | relA | RPA2271 | RPA2693 | Putative Pyruvate kinase; Belongs to the pyruvate kinase family. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.921 |
| RPA4536 | RPA0135 | RPA4536 | RPA0135 | Cyclic nucleotide regulated pyridine nucleotide-disulphide oxidoreductase. | Possible oxidoreductase. | 0.454 |
| RPA4536 | RPA2271 | RPA4536 | RPA2271 | Cyclic nucleotide regulated pyridine nucleotide-disulphide oxidoreductase. | Putative Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.406 |
| RPA4536 | cyaA | RPA4536 | RPA1582 | Cyclic nucleotide regulated pyridine nucleotide-disulphide oxidoreductase. | Ferredoxin:Adenylate/Guanylate cyclase. | 0.915 |
| RPA4536 | nuoCD | RPA4536 | RPA4262 | Cyclic nucleotide regulated pyridine nucleotide-disulphide oxidoreductase. | NADH-ubiquinone dehydrogenase chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.461 |
| RPA4536 | pyk | RPA4536 | RPA4193 | Cyclic nucleotide regulated pyridine nucleotide-disulphide oxidoreductase. | Pyruvate kinase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pyruvate kinase family. | 0.409 |
| cpdA | cpdA-3 | RPA1480 | RPA0125 | Putative ICC protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.929 |
| cpdA | cyaA | RPA1480 | RPA1582 | Putative ICC protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Ferredoxin:Adenylate/Guanylate cyclase. | 0.977 |
| cpdA | mazG | RPA1480 | RPA2811 | Putative ICC protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Possible mazG. | 0.900 |
| cpdA-3 | cpdA | RPA0125 | RPA1480 | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Putative ICC protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.929 |
| cpdA-3 | cyaA | RPA0125 | RPA1582 | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Ferredoxin:Adenylate/Guanylate cyclase. | 0.980 |
| cpdA-3 | mazG | RPA0125 | RPA2811 | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Possible mazG. | 0.901 |