Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RPA1788Possible 4-hydroxybenzoyl-CoA thioesterase. (139 aa)    
Predicted Functional Partners:
hbaA
4-hydroxybenzoate-CoA ligase; Catalyzes the ligation of 4-hydroxybenzoate, benzoate or cyclohex-1,4-dienecarboxylate and CoA at the expense of ATP. The enzyme shows low activity towards cyclo-2,5-dienecarboxylate, 4- fluorobenzoate, 4-chlorobenzoate and 2-methoxybenzoate. Belongs to the ATP-dependent AMP-binding enzyme family. Benzoate-CoA ligase subfamily.
 
 
 0.948
phbH
4-hydroxybenzoate hydroxylase (4-hydroxybenzoate-3-monooxygenase).
 
  
  0.922
ubiA
Putative 4-hydroxybenzoate-octaprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
     
 0.904
hbaD
4-hydroxybenzoyl-CoA reductase, third of three subunits; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
    
  0.903
hbaB
4-hydroxybenzoyl-CoA reductase, first of three subunits.
   
 
  0.902
hbaC
4-hydroxybenzoyl-CoA reductase,second of three subunits.
     
  0.900
cyp199a2
Putative cytochrome P450; The oxidative demethylation of 4-methoxybenzoate requires the participation of the monooxygenase CYP199A2, the ferredoxin-like protein ThcC/RPA1872 and a ferredoxin reductase to mediate the transfer of electrons from NADH to CYP199A2. It is also active with 4- ethylbenzoate.
     
  0.900
fcs2
Putative feruloyl-CoA synthetase.
 
  
 0.833
RPA1789
Putative branched-chain amino acid transport system substrate-binding protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
     0.752
RPA1786
Putative 3-hydroxybutyryl-CoA dehydratase.
 
  
 0.712
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
Server load: medium (52%) [HD]