| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA1244 | cysG | RPA1244 | RPA4215 | Conserved unknown protein. | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.891 |
| RPA1244 | nifU | RPA1244 | RPA4609 | Conserved unknown protein. | Putative nifU protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.950 |
| RPA1244 | oxlT | RPA1244 | RPA1944 | Conserved unknown protein. | Possible oxalate/formate antiporter. | 0.541 |
| RPA1888 | oxlT | RPA1888 | RPA1944 | Putative major capsid protein, R. capsulatus GTA orfg5 homologue; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Possible oxalate/formate antiporter. | 0.684 |
| RPA1946 | frc | RPA1946 | RPA1945 | Possible transcriptional regulator, GntR family. | Putative acyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate (By similarity); Belongs to the CoA-transferase III family. Frc subfamily. | 0.773 |
| RPA1946 | oxlT | RPA1946 | RPA1944 | Possible transcriptional regulator, GntR family. | Possible oxalate/formate antiporter. | 0.731 |
| RPA1946 | panE | RPA1946 | RPA1943 | Possible transcriptional regulator, GntR family. | Putative ketopantoate reductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.428 |
| RPA3797 | cysG | RPA3797 | RPA4215 | Conserved hypothetical protein; COGs COG2068. | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.442 |
| RPA3797 | nifU | RPA3797 | RPA4609 | Conserved hypothetical protein; COGs COG2068. | Putative nifU protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.522 |
| RPA3797 | oxlT | RPA3797 | RPA1944 | Conserved hypothetical protein; COGs COG2068. | Possible oxalate/formate antiporter. | 0.473 |
| alkB | hppA | RPA1722 | RPA2731 | Alkylated DNA repair protein. | H+ translocating pyrophosphate synthase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.741 |
| alkB | oxlT | RPA1722 | RPA1944 | Alkylated DNA repair protein. | Possible oxalate/formate antiporter. | 0.748 |
| alkB | panE | RPA1722 | RPA1943 | Alkylated DNA repair protein. | Putative ketopantoate reductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.626 |
| cysG | RPA1244 | RPA4215 | RPA1244 | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Conserved unknown protein. | 0.891 |
| cysG | RPA3797 | RPA4215 | RPA3797 | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Conserved hypothetical protein; COGs COG2068. | 0.442 |
| cysG | nifU | RPA4215 | RPA4609 | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Putative nifU protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.783 |
| cysG | oxlT | RPA4215 | RPA1944 | Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Possible oxalate/formate antiporter. | 0.763 |
| frc | RPA1946 | RPA1945 | RPA1946 | Putative acyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate (By similarity); Belongs to the CoA-transferase III family. Frc subfamily. | Possible transcriptional regulator, GntR family. | 0.773 |
| frc | oxlT | RPA1945 | RPA1944 | Putative acyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate (By similarity); Belongs to the CoA-transferase III family. Frc subfamily. | Possible oxalate/formate antiporter. | 0.814 |
| frc | panE | RPA1945 | RPA1943 | Putative acyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate (By similarity); Belongs to the CoA-transferase III family. Frc subfamily. | Putative ketopantoate reductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.524 |