| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0789 | RPA2356 | RPA0789 | RPA2356 | Putative serine-glyoxylate aminotransferase. | Putative cystathionine beta-synthase. | 0.921 |
| RPA0789 | RPA3967 | RPA0789 | RPA3967 | Putative serine-glyoxylate aminotransferase. | Putative threonine dehydratase. | 0.930 |
| RPA0789 | glyA1 | RPA0789 | RPA2724 | Putative serine-glyoxylate aminotransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.931 |
| RPA0789 | glyA2 | RPA0789 | RPA2796 | Putative serine-glyoxylate aminotransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.931 |
| RPA0789 | pssA | RPA0789 | RPA2007 | Putative serine-glyoxylate aminotransferase. | Possible phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| RPA0789 | serB | RPA0789 | RPA2029 | Putative serine-glyoxylate aminotransferase. | Putative phosphoserine phosphatase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.936 |
| RPA0789 | trpA | RPA0789 | RPA0070 | Putative serine-glyoxylate aminotransferase. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.921 |
| RPA0789 | trpB | RPA0789 | RPA0069 | Putative serine-glyoxylate aminotransferase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.913 |
| RPA0789 | trpB-1 | RPA0789 | RPA1594 | Putative serine-glyoxylate aminotransferase. | Putative tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| RPA2356 | RPA0789 | RPA2356 | RPA0789 | Putative cystathionine beta-synthase. | Putative serine-glyoxylate aminotransferase. | 0.921 |
| RPA2356 | RPA3967 | RPA2356 | RPA3967 | Putative cystathionine beta-synthase. | Putative threonine dehydratase. | 0.939 |
| RPA2356 | glyA1 | RPA2356 | RPA2724 | Putative cystathionine beta-synthase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.942 |
| RPA2356 | glyA2 | RPA2356 | RPA2796 | Putative cystathionine beta-synthase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.942 |
| RPA2356 | pssA | RPA2356 | RPA2007 | Putative cystathionine beta-synthase. | Possible phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.901 |
| RPA2356 | serB | RPA2356 | RPA2029 | Putative cystathionine beta-synthase. | Putative phosphoserine phosphatase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.928 |
| RPA2356 | trpA | RPA2356 | RPA0070 | Putative cystathionine beta-synthase. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.927 |
| RPA2356 | trpB | RPA2356 | RPA0069 | Putative cystathionine beta-synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.912 |
| RPA2356 | trpB-1 | RPA2356 | RPA1594 | Putative cystathionine beta-synthase. | Putative tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| RPA3967 | RPA0789 | RPA3967 | RPA0789 | Putative threonine dehydratase. | Putative serine-glyoxylate aminotransferase. | 0.930 |
| RPA3967 | RPA2356 | RPA3967 | RPA2356 | Putative threonine dehydratase. | Putative cystathionine beta-synthase. | 0.939 |