node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CbiG | cobB | RPA2085 | RPA2083 | Cobalamin biosynthesis protein G; CbiG. | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.987 |
CbiG | cobF | RPA2085 | RPA2097 | Cobalamin biosynthesis protein G; CbiG. | Putative cobF protein; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.963 |
CbiG | cobH | RPA2085 | RPA2090 | Cobalamin biosynthesis protein G; CbiG. | Precorrin isomerase CobH; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.937 |
CbiG | cobI | RPA2085 | RPA2089 | Cobalamin biosynthesis protein G; CbiG. | Precorrin 2 methylase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the precorrin methyltransferase family. | 0.944 |
CbiG | cobJ | RPA2085 | RPA2088 | Cobalamin biosynthesis protein G; CbiG. | Precorrin 3 methylase. | 0.958 |
CbiG | cobK | RPA2085 | RPA2087 | Cobalamin biosynthesis protein G; CbiG. | Putative precorrin 6x reductase. | 0.979 |
CbiG | cobL | RPA2085 | RPA2086 | Cobalamin biosynthesis protein G; CbiG. | Putative precorrin 6y methylase. | 0.994 |
CbiG | cobM | RPA2085 | RPA2084 | Cobalamin biosynthesis protein G; CbiG. | Precorrin 3 or 4 methylase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.999 |
CbiG | cobO, | RPA2085 | RPA0717 | Cobalamin biosynthesis protein G; CbiG. | Putative cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.509 |
CbiG | cobQ2 | RPA2085 | RPA2096 | Cobalamin biosynthesis protein G; CbiG. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.571 |
cobB | CbiG | RPA2083 | RPA2085 | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthesis protein G; CbiG. | 0.987 |
cobB | cobF | RPA2083 | RPA2097 | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Putative cobF protein; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.934 |
cobB | cobH | RPA2083 | RPA2090 | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin isomerase CobH; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.997 |
cobB | cobI | RPA2083 | RPA2089 | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin 2 methylase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the precorrin methyltransferase family. | 0.881 |
cobB | cobJ | RPA2083 | RPA2088 | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin 3 methylase. | 0.968 |
cobB | cobK | RPA2083 | RPA2087 | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Putative precorrin 6x reductase. | 0.943 |
cobB | cobL | RPA2083 | RPA2086 | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Putative precorrin 6y methylase. | 0.996 |
cobB | cobM | RPA2083 | RPA2084 | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin 3 or 4 methylase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.988 |
cobB | cobO, | RPA2083 | RPA0717 | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Putative cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.989 |
cobB | cobQ2 | RPA2083 | RPA2096 | Putative cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.947 |