Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ilvD3Dihydroxy-acid dehydratase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the IlvD/Edd family. (568 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.880
ilvI
Acetolactate synthase (large subunit); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
 0.873
ilvH
Acetolactate synthase (small subunit); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
 
 0.853
RPA3917
Possible acetolactate synthase large subunit; Belongs to the TPP enzyme family.
 
 
 0.849
RPA0108
Possible benzaldehyde lyase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the TPP enzyme family.
 
 
 0.848
ilvB
Putative acetolactate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the TPP enzyme family.
 
 
 0.846
RPA2760
Possible benzaldehyde lyase; Belongs to the TPP enzyme family.
 
 
 0.837
leuC
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
  
 0.816
RPA4054
Possible acetolactate synthase large subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the TPP enzyme family.
 
 
 0.794
mdlC
Benzoylformate decarboxylase; 75% identity to Bradyrhizobium japonicum probable benzoylformate decarboxylase; Belongs to the TPP enzyme family.
 
 
 0.768
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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