| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA2289 | RPA2290 | RPA2289 | RPA2290 | Hypothetical protein; InterPro IPR001440. | Conserved hypothetical protein. | 0.965 |
| RPA2289 | RPA2291 | RPA2289 | RPA2291 | Hypothetical protein; InterPro IPR001440. | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.821 |
| RPA2290 | RPA2289 | RPA2290 | RPA2289 | Conserved hypothetical protein. | Hypothetical protein; InterPro IPR001440. | 0.965 |
| RPA2290 | RPA2291 | RPA2290 | RPA2291 | Conserved hypothetical protein. | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.918 |
| RPA2291 | RPA2289 | RPA2291 | RPA2289 | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Hypothetical protein; InterPro IPR001440. | 0.821 |
| RPA2291 | RPA2290 | RPA2291 | RPA2290 | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Conserved hypothetical protein. | 0.918 |
| RPA2291 | cpdA-2 | RPA2291 | RPA0124 | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.757 |
| RPA2291 | cpdA-3 | RPA2291 | RPA0125 | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.757 |
| RPA2291 | gch1 | RPA2291 | RPA3391 | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Possible GTP cyclohydrolase I; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.800 |
| RPA2291 | mazG | RPA2291 | RPA2811 | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Possible mazG. | 0.902 |
| RPA2291 | moaA | RPA2291 | RPA1978 | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Molybdenum biosynthetic protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.804 |
| RPA2291 | ndk | RPA2291 | RPA3056 | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Nucleoside-diphosphate-kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.915 |
| RPA2291 | relA | RPA2291 | RPA2693 | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
| RPA2291 | ribB | RPA2291 | RPA1093 | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Possible GTP cyclohydrolase II, riboflavin biosynthesis; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.809 |
| cpdA-2 | RPA2291 | RPA0124 | RPA2291 | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.757 |
| cpdA-2 | cpdA-3 | RPA0124 | RPA0125 | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.825 |
| cpdA-3 | RPA2291 | RPA0125 | RPA2291 | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.757 |
| cpdA-3 | cpdA-2 | RPA0125 | RPA0124 | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.825 |
| cpdA-3 | mazG | RPA0125 | RPA2811 | Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Possible mazG. | 0.901 |
| gch1 | RPA2291 | RPA3391 | RPA2291 | Possible GTP cyclohydrolase I; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative Adenylate/Guanylate cyclase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.800 |