STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB-2Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (253 aa)    
Predicted Functional Partners:
nadE
NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 0.954
nadD
Possible nicotinate-nucleotide adneylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.936
nadK
DUF15 protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.930
RPA0613
NUDIX hydrolase.
  
 0.928
RPA0954
Possible histone deacetylase or acetylpolyamine aminohydrolase or acetoin utilization protein.
   
 
 0.924
pntA-2
Nicotinamide nucleotide transhydrogenase, subunit alpha1; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
     
 0.915
pntA
Nicotinamide nucleotide transhydrogenase, subunit alpha2.
     
 0.908
mazG
Possible mazG.
  
 
  0.903
pntB
Nicotinamide nucleotide transhydrogenase, subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
    
  0.902
RPA4240
GCN5-related N-acetyltransferase:CoA Binding Domain.
  
  
 0.845
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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