Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ntrBNitrogen regulatory signal transduction histidine kinase NtrB; Observed by proteomics; Citation: Foster-Hartnett et al. (1993) Mol. Microbiol. 8:903-914. (390 aa)    
Predicted Functional Partners:
ntrC
Nitrogen assimilation regulatory protein ntrC Response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 0.999
glnB
Nitrogen regulatory protein P-II; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the P(II) protein family.
  
 0.989
nifR3
Putative nitrogen regulation protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
  
 0.920
glnD
Protein PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
  
 
 
 0.897
cckA
Sensor histidine kinase with multiple PAS and a response regulator receiver domain; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
  
 
 0.853
ntrX
Nitrogen assimilation regulatory protein ntrX-Response regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
 0.849
amtB1
Ammonium transporter AmtB.
  
 
 0.813
glnK1
GlnK, nitrogen regulatory protein P-II; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the P(II) protein family.
  
 
 0.777
glnK2
GlnK, nitrogen regulatory protein P-II; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the P(II) protein family.
  
 
 0.777
ntrY
Nitrogen regulatory signal transduction histidine kinase NtrY; Citation: Pawlowski et al. (1991) Mol. Gen. Genet. 231:124-38; observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
  
0.742
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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