Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ntrYNitrogen regulatory signal transduction histidine kinase NtrY; Citation: Pawlowski et al. (1991) Mol. Gen. Genet. 231:124-38; observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. (763 aa)    
Predicted Functional Partners:
ntrX
Nitrogen assimilation regulatory protein ntrX-Response regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 0.999
ntrC
Nitrogen assimilation regulatory protein ntrC Response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 
 0.861
RPA2596
D-alanine aminotransferase.
     
 0.781
ntrB
Nitrogen regulatory signal transduction histidine kinase NtrB; Observed by proteomics; Citation: Foster-Hartnett et al. (1993) Mol. Microbiol. 8:903-914.
 
  
0.742
RPA0043
Possible glutathione S-transferase.
  
   
 0.697
nifR3
Putative nitrogen regulation protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
     
 0.682
lptD
Organic solvent tolerance protein homolog; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
  
     0.676
RPA2927
Possible ABC type permease; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
    0.650
hfq
Probable nfrA protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
     
 0.643
chvI
Two-component transcriptional regulator ChvI, winged helix family; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
 
 
 0.635
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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