| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA1250 | ntrC | RPA1250 | RPA2593 | Amide-urea binding protein. | Nitrogen assimilation regulatory protein ntrC Response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | 0.590 |
| RPA1250 | ntrX | RPA1250 | RPA2595 | Amide-urea binding protein. | Nitrogen assimilation regulatory protein ntrX-Response regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.661 |
| RPA2596 | hflX | RPA2596 | RPA2598 | D-alanine aminotransferase. | GTP binding protein-like; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.670 |
| RPA2596 | hfq | RPA2596 | RPA2597 | D-alanine aminotransferase. | Probable nfrA protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.667 |
| RPA2596 | nifR3 | RPA2596 | RPA2591 | D-alanine aminotransferase. | Putative nitrogen regulation protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.615 |
| RPA2596 | ntrB | RPA2596 | RPA2592 | D-alanine aminotransferase. | Nitrogen regulatory signal transduction histidine kinase NtrB; Observed by proteomics; Citation: Foster-Hartnett et al. (1993) Mol. Microbiol. 8:903-914. | 0.573 |
| RPA2596 | ntrC | RPA2596 | RPA2593 | D-alanine aminotransferase. | Nitrogen assimilation regulatory protein ntrC Response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | 0.588 |
| RPA2596 | ntrX | RPA2596 | RPA2595 | D-alanine aminotransferase. | Nitrogen assimilation regulatory protein ntrX-Response regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.794 |
| RPA2596 | ntrY | RPA2596 | RPA2594 | D-alanine aminotransferase. | Nitrogen regulatory signal transduction histidine kinase NtrY; Citation: Pawlowski et al. (1991) Mol. Gen. Genet. 231:124-38; observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.781 |
| amiC1 | ntrC | RPA2408 | RPA2593 | Putative aliphatic amidase expression-regulating protein, AmiC; Citation: EMBO J 1999 Oct 1;18(19):5175-86. | Nitrogen assimilation regulatory protein ntrC Response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | 0.547 |
| amiC1 | ntrX | RPA2408 | RPA2595 | Putative aliphatic amidase expression-regulating protein, AmiC; Citation: EMBO J 1999 Oct 1;18(19):5175-86. | Nitrogen assimilation regulatory protein ntrX-Response regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.613 |
| hflX | RPA2596 | RPA2598 | RPA2596 | GTP binding protein-like; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | D-alanine aminotransferase. | 0.670 |
| hflX | hfq | RPA2598 | RPA2597 | GTP binding protein-like; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Probable nfrA protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.897 |
| hflX | nifR3 | RPA2598 | RPA2591 | GTP binding protein-like; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Putative nitrogen regulation protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.429 |
| hflX | ntrB | RPA2598 | RPA2592 | GTP binding protein-like; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Nitrogen regulatory signal transduction histidine kinase NtrB; Observed by proteomics; Citation: Foster-Hartnett et al. (1993) Mol. Microbiol. 8:903-914. | 0.442 |
| hflX | ntrC | RPA2598 | RPA2593 | GTP binding protein-like; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Nitrogen assimilation regulatory protein ntrC Response regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | 0.532 |
| hflX | ntrX | RPA2598 | RPA2595 | GTP binding protein-like; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Nitrogen assimilation regulatory protein ntrX-Response regulator; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.597 |
| hflX | ntrY | RPA2598 | RPA2594 | GTP binding protein-like; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Nitrogen regulatory signal transduction histidine kinase NtrY; Citation: Pawlowski et al. (1991) Mol. Gen. Genet. 231:124-38; observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.530 |
| hfq | RPA2596 | RPA2597 | RPA2596 | Probable nfrA protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | D-alanine aminotransferase. | 0.667 |
| hfq | hflX | RPA2597 | RPA2598 | Probable nfrA protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | GTP binding protein-like; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.897 |