| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0078 | glmU | RPA0078 | RPA2659 | Protein of unknown function UPF0079; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.942 |
| RPA0078 | lpxA | RPA0078 | RPA2911 | Protein of unknown function UPF0079; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Acyl-acyl carrier protein-UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.414 |
| RPA0078 | manC, | RPA0078 | RPA3322 | Protein of unknown function UPF0079; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative mannose-1-phosphate guanylyltransferase (GDP) (GDP-mannose pyrophosphorylase) (GMP); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.432 |
| RPA0078 | murA | RPA0078 | RPA4533 | Protein of unknown function UPF0079; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.448 |
| RPA0078 | murD | RPA0078 | RPA3532 | Protein of unknown function UPF0079; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.492 |
| RPA4018 | exoN | RPA4018 | RPA0887 | UDP-glucose-6-dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | UTP-glucose-1-phosphate uridylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.980 |
| RPA4018 | glmS | RPA4018 | RPA2660 | UDP-glucose-6-dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.482 |
| RPA4018 | glmU | RPA4018 | RPA2659 | UDP-glucose-6-dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.875 |
| RPA4018 | manC, | RPA4018 | RPA3322 | UDP-glucose-6-dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative mannose-1-phosphate guanylyltransferase (GDP) (GDP-mannose pyrophosphorylase) (GMP); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.969 |
| exoN | RPA4018 | RPA0887 | RPA4018 | UTP-glucose-1-phosphate uridylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | UDP-glucose-6-dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.980 |
| exoN | glmS | RPA0887 | RPA2660 | UTP-glucose-1-phosphate uridylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.441 |
| exoN | glmU | RPA0887 | RPA2659 | UTP-glucose-1-phosphate uridylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.936 |
| exoN | manC, | RPA0887 | RPA3322 | UTP-glucose-1-phosphate uridylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative mannose-1-phosphate guanylyltransferase (GDP) (GDP-mannose pyrophosphorylase) (GMP); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.930 |
| exoN | mrsA | RPA0887 | RPA4318 | UTP-glucose-1-phosphate uridylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Phosphoglucomutase/phosphomannomutase family protein MrsA; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.559 |
| exoN | murA | RPA0887 | RPA4533 | UTP-glucose-1-phosphate uridylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.869 |
| exoN | ribP | RPA0887 | RPA4362 | UTP-glucose-1-phosphate uridylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.452 |
| glmS | RPA4018 | RPA2660 | RPA4018 | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-glucose-6-dehydrogenase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.482 |
| glmS | exoN | RPA2660 | RPA0887 | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UTP-glucose-1-phosphate uridylyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.441 |
| glmS | glmU | RPA2660 | RPA2659 | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.980 |
| glmS | manC, | RPA2660 | RPA3322 | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Putative mannose-1-phosphate guanylyltransferase (GDP) (GDP-mannose pyrophosphorylase) (GMP); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.942 |