RPA2895 protein (Rhodopseudomonas palustris CGA009)

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Score

RPA2895

Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family. (166 aa)

Predicted Functional Partners:

clpB

0.806

clpA

0.774

hspD

0.741

dnaK

0.674

htpG

0.605

RPA0369

0.604

grpE

0.563

hslV

0.541

RPA2894

0.528

hslU

0.512

Your Current Organism:

Rhodopseudomonas palustris CGA009

NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RPA0369	RPA2895	RPA0369	RPA2895	Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like.	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	0.604
RPA0369	clpA	RPA0369	RPA3147	Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like.	Endopeptidase Clp: ATP-binding chain A; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the ClpA/ClpB family.	0.705
RPA0369	clpB	RPA0369	RPA4433	Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like.	Endopeptidase Clp: ATP-binding subunit B, clpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the C [...]	0.704
RPA0369	dnaK	RPA0369	RPA0333	Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like.	Heat shock protein DnaK (70); Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.994
RPA0369	grpE	RPA0369	RPA0331	Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like.	Possible heat shock protein (HSP-70 COFACTOR), grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction c [...]	0.851
RPA0369	hslU	RPA0369	RPA0306	Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like.	Heat shock protein HslU, proteasome-related ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.	0.841
RPA0369	hslV	RPA0369	RPA0308	Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like.	Heat shock protein HslV, proteasome-related peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.	0.848
RPA0369	hspD	RPA0369	RPA0889	Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like.	Small heat shock protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the small heat shock protein (HSP20) family.	0.599
RPA2894	RPA2895	RPA2894	RPA2895	Conserved hypothetical protein.	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	0.528
RPA2895	RPA0369	RPA2895	RPA0369	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like.	0.604
RPA2895	RPA2894	RPA2895	RPA2894	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Conserved hypothetical protein.	0.528
RPA2895	clpA	RPA2895	RPA3147	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Endopeptidase Clp: ATP-binding chain A; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the ClpA/ClpB family.	0.774
RPA2895	clpB	RPA2895	RPA4433	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Endopeptidase Clp: ATP-binding subunit B, clpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the C [...]	0.806
RPA2895	dnaK	RPA2895	RPA0333	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein DnaK (70); Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.674
RPA2895	grpE	RPA2895	RPA0331	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Possible heat shock protein (HSP-70 COFACTOR), grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction c [...]	0.563
RPA2895	hslU	RPA2895	RPA0306	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein HslU, proteasome-related ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.	0.512
RPA2895	hslV	RPA2895	RPA0308	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein HslV, proteasome-related peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.	0.541
RPA2895	hspD	RPA2895	RPA0889	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Small heat shock protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the small heat shock protein (HSP20) family.	0.741
RPA2895	htpG	RPA2895	RPA4815	Possible small heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.	0.605
clpA	RPA0369	RPA3147	RPA0369	Endopeptidase Clp: ATP-binding chain A; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the ClpA/ClpB family.	Aminoacyl-tRNA synthetase, class I:ATP-binding region, ATPase-like.	0.705