node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPA2910 | bamA | RPA2910 | RPA2914 | Conserved hypothetical protein; COGs COG3494. | Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.785 |
RPA2910 | fabZ | RPA2910 | RPA2912 | Conserved hypothetical protein; COGs COG3494. | Possible (3R)-hydroxymyristoyl-acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.799 |
RPA2910 | kpsF | RPA2910 | RPA0879 | Conserved hypothetical protein; COGs COG3494. | CBS domain:Sugar isomerase (SIS):KpsF/GutQ family protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.746 |
RPA2910 | lpxA | RPA2910 | RPA2911 | Conserved hypothetical protein; COGs COG3494. | Acyl-acyl carrier protein-UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.953 |
RPA2910 | lpxB | RPA2910 | RPA2909 | Conserved hypothetical protein; COGs COG3494. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.992 |
RPA2910 | lpxC | RPA2910 | RPA3521 | Conserved hypothetical protein; COGs COG3494. | Putative UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosmine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.809 |
RPA2910 | lpxD | RPA2910 | RPA2913 | Conserved hypothetical protein; COGs COG3494. | UDP-3-o-[3-hydroxymyristoyl] glucosamine n-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.945 |
acpP | fabZ | RPA3073 | RPA2912 | Constitutive acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Possible (3R)-hydroxymyristoyl-acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.933 |
acpP | lpxD | RPA3073 | RPA2913 | Constitutive acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | UDP-3-o-[3-hydroxymyristoyl] glucosamine n-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.899 |
acpP | rpsB | RPA3073 | RPA2922 | Constitutive acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 30S ribosomal protein S2; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the universal ribosomal protein uS2 family. | 0.587 |
bamA | RPA2910 | RPA2914 | RPA2910 | Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Conserved hypothetical protein; COGs COG3494. | 0.785 |
bamA | fabZ | RPA2914 | RPA2912 | Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Possible (3R)-hydroxymyristoyl-acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.873 |
bamA | kpsF | RPA2914 | RPA0879 | Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | CBS domain:Sugar isomerase (SIS):KpsF/GutQ family protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.445 |
bamA | lpxA | RPA2914 | RPA2911 | Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Acyl-acyl carrier protein-UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.937 |
bamA | lpxB | RPA2914 | RPA2909 | Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.798 |
bamA | lpxC | RPA2914 | RPA3521 | Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosmine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.636 |
bamA | lpxD | RPA2914 | RPA2913 | Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | UDP-3-o-[3-hydroxymyristoyl] glucosamine n-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.963 |
bamA | pyrH | RPA2914 | RPA2920 | Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.844 |
bamA | rpsB | RPA2914 | RPA2922 | Putative outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 30S ribosomal protein S2; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the universal ribosomal protein uS2 family. | 0.729 |
fabZ | RPA2910 | RPA2912 | RPA2910 | Possible (3R)-hydroxymyristoyl-acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | Conserved hypothetical protein; COGs COG3494. | 0.799 |