| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0418 | gpt | RPA0418 | RPA2179 | Glutamine amidotransferase class-I. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.906 |
| RPA0418 | guaA | RPA0418 | RPA2203 | Glutamine amidotransferase class-I. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.908 |
| RPA0418 | guaC | RPA0418 | RPA4561 | Glutamine amidotransferase class-I. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.942 |
| RPA0418 | kguA | RPA0418 | RPA3069 | Glutamine amidotransferase class-I. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.914 |
| RPA0418 | surE | RPA0418 | RPA2841 | Glutamine amidotransferase class-I. | Survival protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.910 |
| RPA3070 | kguA | RPA3070 | RPA3069 | Conserved unknown protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.978 |
| gpt | RPA0418 | RPA2179 | RPA0418 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Glutamine amidotransferase class-I. | 0.906 |
| gpt | guaA | RPA2179 | RPA2203 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.933 |
| gpt | guaC | RPA2179 | RPA4561 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.917 |
| gpt | kguA | RPA2179 | RPA3069 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.928 |
| gpt | surE | RPA2179 | RPA2841 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Survival protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| guaA | RPA0418 | RPA2203 | RPA0418 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Glutamine amidotransferase class-I. | 0.908 |
| guaA | gpt | RPA2203 | RPA2179 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.933 |
| guaA | guaC | RPA2203 | RPA4561 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.997 |
| guaA | kguA | RPA2203 | RPA3069 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.969 |
| guaA | ndk | RPA2203 | RPA3056 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Nucleoside-diphosphate-kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.574 |
| guaA | nrd | RPA2203 | RPA2977 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.548 |
| guaA | purB | RPA2203 | RPA3817 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.932 |
| guaA | surE | RPA2203 | RPA2841 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Survival protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.955 |
| guaC | RPA0418 | RPA4561 | RPA0418 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Glutamine amidotransferase class-I. | 0.942 |