kguA protein (Rhodopseudomonas palustris CGA009)

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Score

kguA

Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (220 aa)

Predicted Functional Partners:

RPA3070

0.983

guaA

0.973

apt

0.970

pyk

0.938

ndk

0.936

RPA3814

0.936

guaC

0.929

relA

0.927

eno

0.926

RPA2271

0.924

Your Current Organism:

Rhodopseudomonas palustris CGA009

NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RPA2271	eno	RPA2271	RPA2874	Putative Pyruvate kinase; Belongs to the pyruvate kinase family.	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	0.990
RPA2271	guaA	RPA2271	RPA2203	Putative Pyruvate kinase; Belongs to the pyruvate kinase family.	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	0.503
RPA2271	guaC	RPA2271	RPA4561	Putative Pyruvate kinase; Belongs to the pyruvate kinase family.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.471
RPA2271	kguA	RPA2271	RPA3069	Putative Pyruvate kinase; Belongs to the pyruvate kinase family.	Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.924
RPA2271	ndk	RPA2271	RPA3056	Putative Pyruvate kinase; Belongs to the pyruvate kinase family.	Nucleoside-diphosphate-kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.910
RPA2271	pyk	RPA2271	RPA4193	Putative Pyruvate kinase; Belongs to the pyruvate kinase family.	Pyruvate kinase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pyruvate kinase family.	0.926
RPA2271	relA	RPA2271	RPA2693	Putative Pyruvate kinase; Belongs to the pyruvate kinase family.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.921
RPA3070	kguA	RPA3070	RPA3069	Conserved unknown protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.983
RPA3814	eno	RPA3814	RPA2874	Calcium-binding EF-hand; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	0.440
RPA3814	kguA	RPA3814	RPA3069	Calcium-binding EF-hand; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.936
RPA3814	ndk	RPA3814	RPA3056	Calcium-binding EF-hand; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	Nucleoside-diphosphate-kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.886
apt	guaA	RPA4492	RPA2203	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	0.992
apt	guaC	RPA4492	RPA4561	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.943
apt	kguA	RPA4492	RPA3069	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.970
apt	ndk	RPA4492	RPA3056	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Nucleoside-diphosphate-kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.413
eno	RPA2271	RPA2874	RPA2271	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	Putative Pyruvate kinase; Belongs to the pyruvate kinase family.	0.990
eno	RPA3814	RPA2874	RPA3814	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	Calcium-binding EF-hand; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	0.440
eno	guaA	RPA2874	RPA2203	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	0.572
eno	kguA	RPA2874	RPA3069	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.926
eno	ndk	RPA2874	RPA3056	Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.	Nucleoside-diphosphate-kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.525