Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (274 aa)    
Predicted Functional Partners:
panC
Putative pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.999
apbA/panE
Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
 0.990
ilvE
Putative branched-chain amino acid aminotransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
    
 0.920
RPA4593
Possible branched-chain amino acid aminotransferase.
    
 0.920
panE1
Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.919
panE
Putative ketopantoate reductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
    
 0.919
ilvD2
Dihydroxy-acid dehydratase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the IlvD/Edd family.
    
 0.910
ilvD
Putative dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
    
 0.910
RPA3099
Conserved hypothetical protein; InterPro IPR001092.
  
    0.868
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
   
  
 0.807
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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