| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| rluC | rplC | RPA3208 | RPA3250 | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.841 |
| rluC | rplK | RPA3208 | RPA3273 | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.736 |
| rluC | rplM, | RPA3208 | RPA2767 | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.822 |
| rluC | rplN | RPA3208 | RPA3240 | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome. | 0.721 |
| rluC | rplO | RPA3208 | RPA3231 | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L15; Binds to the 23S rRNA. | 0.846 |
| rluC | rplQ | RPA3208 | RPA3225 | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L17; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.808 |
| rluC | rplU, | RPA3208 | RPA0158 | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | Putative ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20. | 0.737 |
| rluC | rplX | RPA3208 | RPA3239 | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL24 family. | 0.814 |
| rluC | rrm1 | RPA3208 | RPA3364 | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | Putative rRNA methylase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.809 |
| rluC | rsfS | RPA3208 | RPA0166 | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.750 |
| rplC | rluC | RPA3250 | RPA3208 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Possible ribosomal large subunit pseudouridine synthase C; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the pseudouridine synthase RluA family. | 0.841 |
| rplC | rplK | RPA3250 | RPA3273 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.997 |
| rplC | rplM, | RPA3250 | RPA2767 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.998 |
| rplC | rplN | RPA3250 | RPA3240 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome. | 0.999 |
| rplC | rplO | RPA3250 | RPA3231 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L15; Binds to the 23S rRNA. | 0.998 |
| rplC | rplQ | RPA3250 | RPA3225 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L17; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.997 |
| rplC | rplU, | RPA3250 | RPA0158 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Putative ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20. | 0.992 |
| rplC | rplX | RPA3250 | RPA3239 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL24 family. | 0.998 |
| rplC | rrm1 | RPA3250 | RPA3364 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Putative rRNA methylase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.885 |
| rplC | rsfS | RPA3250 | RPA0166 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.892 |
