nadK protein (Rhodopseudomonas palustris CGA009)

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nadK

DUF15 protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (328 aa)

Predicted Functional Partners:

nadE

0.962

nadD

0.943

cobB-2

0.927

pntA-2

0.920

pntA

0.919

pntB

0.912

RPA0613

0.904

mazG

0.900

RPA3499

0.693

mao

0.686

Your Current Organism:

Rhodopseudomonas palustris CGA009

NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RPA0613	cobB-2	RPA0613	RPA2524	NUDIX hydrolase.	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.928
RPA0613	mazG	RPA0613	RPA2811	NUDIX hydrolase.	Possible mazG.	0.912
RPA0613	nadD	RPA0613	RPA0165	NUDIX hydrolase.	Possible nicotinate-nucleotide adneylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.909
RPA0613	nadE	RPA0613	RPA1986	NUDIX hydrolase.	NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.913
RPA0613	nadK	RPA0613	RPA3374	NUDIX hydrolase.	DUF15 protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.904
RPA0613	pntA	RPA0613	RPA4181	NUDIX hydrolase.	Nicotinamide nucleotide transhydrogenase, subunit alpha2.	0.900
RPA0613	pntA-2	RPA0613	RPA4182	NUDIX hydrolase.	Nicotinamide nucleotide transhydrogenase, subunit alpha1; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	0.900
RPA0613	pntB	RPA0613	RPA4180	NUDIX hydrolase.	Nicotinamide nucleotide transhydrogenase, subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.900
RPA3499	nadK	RPA3499	RPA3374	Conserved unknown protein.	DUF15 protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.693
cobB-2	RPA0613	RPA2524	RPA0613	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	NUDIX hydrolase.	0.928
cobB-2	mao	RPA2524	RPA3042	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Malate oxidoreductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	0.662
cobB-2	mazG	RPA2524	RPA2811	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Possible mazG.	0.902
cobB-2	nadD	RPA2524	RPA0165	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Possible nicotinate-nucleotide adneylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.937
cobB-2	nadE	RPA2524	RPA1986	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.954
cobB-2	nadK	RPA2524	RPA3374	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	DUF15 protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.927
cobB-2	pntA	RPA2524	RPA4181	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Nicotinamide nucleotide transhydrogenase, subunit alpha2.	0.904
cobB-2	pntA-2	RPA2524	RPA4182	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Nicotinamide nucleotide transhydrogenase, subunit alpha1; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	0.904
cobB-2	pntB	RPA2524	RPA4180	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Nicotinamide nucleotide transhydrogenase, subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.902
mao	cobB-2	RPA3042	RPA2524	Malate oxidoreductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.662
mao	nadK	RPA3042	RPA3374	Malate oxidoreductase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	DUF15 protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.686

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