node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPA3670 | hrpB | RPA3670 | RPA0535 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Putative ATP-dependent helicase. | 0.807 |
RPA3670 | infA | RPA3670 | RPA3671 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Translation initiation factor if-1 (infA); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.903 |
RPA3670 | pnp | RPA3670 | RPA0432 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.836 |
RPA3670 | rplC | RPA3670 | RPA3250 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.833 |
RPA3670 | rplD | RPA3670 | RPA3249 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.776 |
RPA3670 | rplM, | RPA3670 | RPA2767 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.794 |
RPA3670 | rplX | RPA3670 | RPA3239 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL24 family. | 0.806 |
RPA3670 | rpsD | RPA3670 | RPA1589 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.806 |
RPA3670 | thiD | RPA3670 | RPA3971 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Phosphomethylpyrimidine kinase (hmp-phosphate kinase); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. | 0.828 |
RPA3670 | yjeF | RPA3670 | RPA2965 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | Protein of unknown function UPF0031:YjeF-related protein, N-terminal; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hyd [...] | 0.881 |
hrpB | RPA3670 | RPA0535 | RPA3670 | Putative ATP-dependent helicase. | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 0.807 |
hrpB | rplD | RPA0535 | RPA3249 | Putative ATP-dependent helicase. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.715 |
hrpB | rpsD | RPA0535 | RPA1589 | Putative ATP-dependent helicase. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.947 |
infA | RPA3670 | RPA3671 | RPA3670 | Translation initiation factor if-1 (infA); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. | 0.903 |
infA | pnp | RPA3671 | RPA0432 | Translation initiation factor if-1 (infA); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.432 |
infA | rplC | RPA3671 | RPA3250 | Translation initiation factor if-1 (infA); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.971 |
infA | rplD | RPA3671 | RPA3249 | Translation initiation factor if-1 (infA); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.997 |
infA | rplM, | RPA3671 | RPA2767 | Translation initiation factor if-1 (infA); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.935 |
infA | rplX | RPA3671 | RPA3239 | Translation initiation factor if-1 (infA); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL24 family. | 0.987 |
infA | rpsD | RPA3671 | RPA1589 | Translation initiation factor if-1 (infA); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.997 |