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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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ahcYS-adenosyl L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (469 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
 
 
 0.973
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.966
RPA2181
Possible metE (5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase); Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
  
 
 0.962
RPA2356
Putative cystathionine beta-synthase.
  
 0.951
metK
Methionine S-adenosyltransferase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the AdoMet synthase family.
 
 
 0.948
metC-2
Cystathionine beta-lyase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
  
 0.921
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.921
dcm
Possible site-specific DNA-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.906
RPA1569
O-acetylhomoserine sulfhydrylase; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
     
 0.906
metY
Putative homocysteine synthase.
     
 0.906
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
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