pntA-2 protein (Rhodopseudomonas palustris CGA009)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

pntA-2

Nicotinamide nucleotide transhydrogenase, subunit alpha1; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished. (375 aa)

Predicted Functional Partners:

pntB

0.999

pntA

0.999

nadK

0.920

nadE

0.908

nadD

0.904

cobB-2

0.904

mazG

0.902

RPA0613

0.900

ubiB

0.765

mutT

0.753

Your Current Organism:

Rhodopseudomonas palustris CGA009

NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RPA0613	cobB-2	RPA0613	RPA2524	NUDIX hydrolase.	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.928
RPA0613	mazG	RPA0613	RPA2811	NUDIX hydrolase.	Possible mazG.	0.912
RPA0613	nadD	RPA0613	RPA0165	NUDIX hydrolase.	Possible nicotinate-nucleotide adneylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.909
RPA0613	nadE	RPA0613	RPA1986	NUDIX hydrolase.	NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.913
RPA0613	nadK	RPA0613	RPA3374	NUDIX hydrolase.	DUF15 protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.904
RPA0613	pntA	RPA0613	RPA4181	NUDIX hydrolase.	Nicotinamide nucleotide transhydrogenase, subunit alpha2.	0.900
RPA0613	pntA-2	RPA0613	RPA4182	NUDIX hydrolase.	Nicotinamide nucleotide transhydrogenase, subunit alpha1; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	0.900
RPA0613	pntB	RPA0613	RPA4180	NUDIX hydrolase.	Nicotinamide nucleotide transhydrogenase, subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.900
cobB-2	RPA0613	RPA2524	RPA0613	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	NUDIX hydrolase.	0.928
cobB-2	mazG	RPA2524	RPA2811	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Possible mazG.	0.902
cobB-2	nadD	RPA2524	RPA0165	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Possible nicotinate-nucleotide adneylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.937
cobB-2	nadE	RPA2524	RPA1986	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.954
cobB-2	nadK	RPA2524	RPA3374	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	DUF15 protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.927
cobB-2	pntA	RPA2524	RPA4181	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Nicotinamide nucleotide transhydrogenase, subunit alpha2.	0.904
cobB-2	pntA-2	RPA2524	RPA4182	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Nicotinamide nucleotide transhydrogenase, subunit alpha1; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.	0.904
cobB-2	pntB	RPA2524	RPA4180	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Nicotinamide nucleotide transhydrogenase, subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.902
mazG	RPA0613	RPA2811	RPA0613	Possible mazG.	NUDIX hydrolase.	0.912
mazG	cobB-2	RPA2811	RPA2524	Possible mazG.	Sir2 family, possible ADP ribosyltransferase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.902
mazG	nadD	RPA2811	RPA0165	Possible mazG.	Possible nicotinate-nucleotide adneylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.907
mazG	nadE	RPA2811	RPA1986	Possible mazG.	NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.902

page 1 of 4

Server load: medium (48%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About