Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RPA4212Conserved hypothetical protein. (169 aa)    
Predicted Functional Partners:
RPA4213
Sulfite reductase hemoprotein subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
  
 0.996
RPA4214
Conserved hypothetical protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
 
    0.918
cysG
Putative siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.917
cysN
Putative CysN/CysC bifunctional enzyme, ATP-sulfurylase large subunit and adenylyl sulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.805
nirA
Possible ferredoxin-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.789
cysH
Putative phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
 
  
 0.782
cysA
Putative sulfate ABC transporter, ATP-binding component; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
  
  
 0.614
cysD
Putative ATP sulfurylase small subunit; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
  
  
 0.560
cysW
Possible sulfate ABC transporter, permease component.
  
  
 0.511
RPA0608
Conserved unknown protein; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished.
  
     0.492
Your Current Organism:
Rhodopseudomonas palustris CGA009
NCBI taxonomy Id: 258594
Other names: R. palustris CGA009, Rhodopseudomonas palustris str. CGA009, Rhodopseudomonas palustris strain CGA009
Server load: low (36%) [HD]