| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RPA0285 | RPA4360 | RPA0285 | RPA4360 | Protein of unknown function UPF0001; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.732 |
| RPA0955 | RPA4360 | RPA0955 | RPA4360 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.900 |
| RPA0955 | apt | RPA0955 | RPA4492 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.926 |
| RPA0955 | gpt | RPA0955 | RPA2179 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.904 |
| RPA0955 | surE | RPA0955 | RPA2841 | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | Survival protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
| RPA2908 | RPA4360 | RPA2908 | RPA4360 | Cytidine/deoxycytidylate deaminase:Tat pathway signal. | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.903 |
| RPA2908 | gpt | RPA2908 | RPA2179 | Cytidine/deoxycytidylate deaminase:Tat pathway signal. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.901 |
| RPA4359 | RPA4360 | RPA4359 | RPA4360 | DUF185. | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.904 |
| RPA4359 | lgt | RPA4359 | RPA4358 | DUF185. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.893 |
| RPA4360 | RPA0285 | RPA4360 | RPA0285 | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | Protein of unknown function UPF0001; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.732 |
| RPA4360 | RPA0955 | RPA4360 | RPA0955 | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | 0.900 |
| RPA4360 | RPA2908 | RPA4360 | RPA2908 | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | Cytidine/deoxycytidylate deaminase:Tat pathway signal. | 0.903 |
| RPA4360 | RPA4359 | RPA4360 | RPA4359 | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | DUF185. | 0.904 |
| RPA4360 | apt | RPA4360 | RPA4492 | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.913 |
| RPA4360 | eIF-2B | RPA4360 | RPA4820 | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | Translation initiation factor, aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.903 |
| RPA4360 | gpt | RPA4360 | RPA2179 | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.903 |
| RPA4360 | lgt | RPA4360 | RPA4358 | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.893 |
| RPA4360 | mtnP | RPA4360 | RPA4821 | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | Putative 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.905 |
| RPA4360 | surE | RPA4360 | RPA2841 | DUF152; Observed by proteomics; Citation: Proteomics from VerBerkmoes et al. (2003) unpublished; Belongs to the multicopper oxidase YfiH/RL5 family. | Survival protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.902 |
| apt | RPA0955 | RPA4492 | RPA0955 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative 5`-nucleotidase family protein; Belongs to the 5'-nucleotidase family. | 0.926 |